| Literature DB >> 15681275 |
Jens E Haag1, Alain Vande Wouwer, Philippe Bogaerts.
Abstract
In this study, a class of dynamic models based on metabolic reaction pathways is analyzed, showing that systems with complex intracellular reaction networks can be represented by macroscopic reactions relating extracellular components only. Based on rigorous assumptions, the model reduction procedure is systematic and allows an equivalent 'input-output' representation of the system to be derived. The procedure is illustrated with a few examples.Mesh:
Year: 2004 PMID: 15681275 DOI: 10.1016/j.mbs.2004.11.007
Source DB: PubMed Journal: Math Biosci ISSN: 0025-5564 Impact factor: 2.144