Literature DB >> 15679789

The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects.

Christopher R Chapple1, Walter Artibani, Linda D Cardozo, David Castro-Diaz, Michael Craggs, Francois Haab, Vik Khullar, Eboo Versi.   

Abstract

OBJECTIVE: To review the concept of urinary urgency and its practical measurement in clinical trials, and advance the hypothesis that while urge is experienced by normal people, urgency is always pathological.
METHODS: According to the International Continence Society (ICS) definition, urgency is the primary symptom of the overactive bladder (OAB) syndrome, but in clinical trials there are inconsistencies in both the definition and assessment of urgency. We searched the PubMed and BIOSIS databases for publications and abstracts related to the clinical assessment of urgency in patients with OAB.
RESULTS: The differentiation of urgency from the normal physiological desire to void is discussed. In clinical studies of OAB, urgency has been measured both qualitatively and quantitatively. Existing qualitative assessment scales for urgency are deficient in accuracy, validation or both, and are largely inconsistent with the currently accepted ICS definition of urgency. The quantitative assessment of urgency by diary entry has been validated and may be the most accurate, reproducible and clinically meaningful method available for measuring this variable.
CONCLUSION: Based on the existing ICS definition of urgency as 'a compelling desire to pass urine that is difficult to defer', the concept of qualitative assessment of urgency may be flawed.

Entities:  

Mesh:

Year:  2005        PMID: 15679789     DOI: 10.1111/j.1464-410X.2005.05294.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  37 in total

1.  Validity and reliability of patient selected goals as an outcome measure in overactive bladder.

Authors:  Rufus Cartwright; Sushma Srikrishna; Linda Cardozo; Dudley Robinson
Journal:  Int Urogynecol J       Date:  2011-01-29       Impact factor: 2.894

2.  Urinary nerve growth factor and a variable solifenacin dosage in patients with an overactive bladder.

Authors:  Seyfettin Ciftci; Cuneyd Ozkurkcugil; Hasan Yilmaz; Murat Ustuner; Ufuk Yavuz; Mustafa Yuksekkaya; Mustafa Baki Cekmen
Journal:  Int Urogynecol J       Date:  2015-08-27       Impact factor: 2.894

3.  Solifenacin for overactive bladder: secondary analysis of data from VENUS based on baseline continence status.

Authors:  Marc R Toglia; Donald R Ostergard; Rodney A Appell; Masakazu Andoh; Allam Fakhoury; Iqbal F Hussain
Journal:  Int Urogynecol J       Date:  2010-03-26       Impact factor: 2.894

Review 4.  Measuring urgency in clinical practice.

Authors:  Roger R Dmochowski; Mary P FitzGerald; Jean-Jacques Wyndaele
Journal:  World J Urol       Date:  2009-08-27       Impact factor: 4.226

5.  Urgency as the cardinal symptom of overactive bladder: a critical analysis.

Authors:  Linda Cardozo; Chris Chapple; Alan Wein
Journal:  World J Urol       Date:  2009-11-15       Impact factor: 4.226

6.  Overactive bladder: a new paradigm.

Authors:  Jerry G Blaivas
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2009-10-29

Review 7.  The placebo effect in overactive bladder syndrome.

Authors:  Altaf Mangera; Christopher R Chapple; Zoe S Kopp; Melanie Plested
Journal:  Nat Rev Urol       Date:  2011-07-05       Impact factor: 14.432

Review 8.  The efficacy of mirabegron in the treatment of urgency and the potential utility of combination therapy.

Authors:  Karl-Erik Andersson; Nurul Choudhury; Jean-Nicolas Cornu; Moses Huang; Cees Korstanje; Emad Siddiqui; Philip Van Kerrebroeck
Journal:  Ther Adv Urol       Date:  2018-07-06

9.  Reproducibility study of Overactive Bladder Symptom Score questionnaire and its response to treatment (RESORT) in Korean population with overactive bladder symptoms.

Authors:  Seong Jin Jeong; Yukio Homma; Seung-June Oh
Journal:  Qual Life Res       Date:  2013-05-29       Impact factor: 4.147

10.  Do women with overactive bladder have realistic expectations for therapy?

Authors:  Arasee Renganathan; Dudley Robinson; Linda Cardozo; Sushma Srikrishna; Rufus Cartwright
Journal:  Int Urogynecol J       Date:  2010-04       Impact factor: 2.894

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