A desmoplastic granular cell tumour of the oral cavity: report of a case.

A case of granular cell tumour of the buccal mucosa demonstrating marked desmoplasia is presented. The bulk of the tumour is composed of dense collagenous stroma, which surrounds isolated nests of tumour cells. Since the histomorphologic appearance of this variant is different from that usually seen in this lesion, the diagnosis is supported by immunohistochemical demonstration of S-100 and Vimentin in the tumour cells. The authors believe that this case represents the first report of a desmoplastic granular cell tumour of the oral tissues.