BACKGROUND: Frequent follow-up and regular investigation are routine in pediatric oncology. However, there is little evidence regarding their value in the detection of recurrent disease. METHODS: The authors carried out a retrospective study of the follow-up of 186 children with solid tumors who were diagnosed between 1992 and 1996. The numbers of clinic visits, follow-up investigations, and (if appropriate) the mode of recurrence detection were recorded. RESULTS: The mean follow-up was 5.9 years. During this time, 37 recurrences were detected, symptomatically in 54% of patients, by routine investigation in 30% of patients, and at routine clinic appointment in 16% of patients. It was calculated that routine magnetic resonance imaging detected 1 recurrence for every 42 scans performed, routine computed tomography detected 1 recurrence for every 129 scans performed, and routine chest radiography detected 1 recurrence for every 257 films. CONCLUSIONS: The current results raise questions regarding the usefulness of such follow-up in children with solid tumors.
BACKGROUND: Frequent follow-up and regular investigation are routine in pediatric oncology. However, there is little evidence regarding their value in the detection of recurrent disease. METHODS: The authors carried out a retrospective study of the follow-up of 186 children with solid tumors who were diagnosed between 1992 and 1996. The numbers of clinic visits, follow-up investigations, and (if appropriate) the mode of recurrence detection were recorded. RESULTS: The mean follow-up was 5.9 years. During this time, 37 recurrences were detected, symptomatically in 54% of patients, by routine investigation in 30% of patients, and at routine clinic appointment in 16% of patients. It was calculated that routine magnetic resonance imaging detected 1 recurrence for every 42 scans performed, routine computed tomography detected 1 recurrence for every 129 scans performed, and routine chest radiography detected 1 recurrence for every 257 films. CONCLUSIONS: The current results raise questions regarding the usefulness of such follow-up in children with solid tumors.
Authors: Sue C Kaste; Samuel L Brady; Brian Yee; Valerie J McPherson; Robert A Kaufman; Catherine A Billups; Najat C Daw; Alberto S Pappo Journal: Cancer Date: 2012-06-26 Impact factor: 6.860
Authors: Sara M Federico; Samuel L Brady; Alberto Pappo; Jianrong Wu; Shenghua Mao; Valerie J McPherson; Alison Young; Wayne L Furman; Robert Kaufman; Sue Kaste Journal: Pediatr Blood Cancer Date: 2015-01-13 Impact factor: 3.167
Authors: Deema Hussein; Wiyada Punjaruk; Lisa C D Storer; Lucy Shaw; Ramadhan Othman; Ramadan Ottoman; Andrew Peet; Suzanne Miller; Gagori Bandopadhyay; Rachel Heath; Rajendra Kumari; Karen J Bowman; Paul Braker; Ruman Rahman; George D D Jones; Susan Watson; James Lowe; Ian D Kerr; Richard G Grundy; Beth Coyle Journal: Neuro Oncol Date: 2010-10-25 Impact factor: 12.300