Literature DB >> 15674823

Placental expression of the nuclear receptors for oxysterols LXRalpha and LXRbeta during mouse and human development.

Geoffroy Marceau1, David H Volle, Denis Gallot, David J Mangelsdorf, Vincent Sapin, Jean-Marc A Lobaccaro.   

Abstract

Ontogenesis and localization expression of genes encoding for the nuclear receptors for oxysterols (lxralpha and lxrbeta) were investigated in human and mouse placenta during gestation. Both mRNAs were detectable in the placentation throughout the gestation (from 7 days postcoitum and 6th week of gestation in mouse and human, respectively) by Northern blots or RT-PCR experiments. Lxralpha showed a higher accumulation in the mouse yolk sac. In situ hybridization pointed a specific expression of lxralpha in the human amniotic membranes.

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Year:  2005        PMID： 15674823     DOI： 10.1002/ar.a.20157

Source DB:  PubMed          Journal:  Anat Rec A Discov Mol Cell Evol Biol        ISSN： 1552-4884


  11 in total

1.  RXRα and LXR activate two promoters in placenta- and tumor-specific expression of PLAC1.

Authors:  Y Chen; A Moradin; D Schlessinger; R Nagaraja
Journal:  Placenta       Date:  2011-09-19       Impact factor: 3.481

2.  Metabolism of cholesterol and progesterone is differentially regulated in primary trophoblastic subtypes and might be disturbed in recurrent miscarriages.

Authors:  Sigrid Vondra; Victoria Kunihs; Tanja Eberhart; Karin Eigner; Raimund Bauer; Peter Haslinger; Sandra Haider; Karin Windsperger; Günter Klambauer; Birgit Schütz; Mario Mikula; Xiaowei Zhu; Alexander E Urban; Roberta L Hannibal; Julie Baker; Martin Knöfler; Herbert Stangl; Jürgen Pollheimer; Clemens Röhrl
Journal:  J Lipid Res       Date:  2019-09-17       Impact factor: 5.922

3.  Lxr regulates lipid metabolic and visual perception pathways during zebrafish development.

Authors:  Caroline Lucia Pinto; Sharanya Maanasi Kalasekar; Catherine W McCollum; Anne Riu; Philip Jonsson; Justin Lopez; Eric C Swindell; Abdel Bouhlatouf; Patrick Balaguer; Maria Bondesson; Jan-Åke Gustafsson
Journal:  Mol Cell Endocrinol       Date:  2015-09-30       Impact factor: 4.102

4.  The influence of ligand-activated LXR on primary human trophoblasts.

Authors:  J C Larkin; S B Sears; Y Sadovsky
Journal:  Placenta       Date:  2014-09-10       Impact factor: 3.481

5.  A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.

Authors:  Kevin Mouzat; Eric Mercier; Anne Polge; Alexandre Evrard; Silvère Baron; Jean-Pierre Balducchi; Jean-Paul Brouillet; Serge Lumbroso; Jean-Christophe Gris
Journal:  BMC Med Genet       Date:  2011-10-26       Impact factor: 2.103

6.  Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.

Authors:  Marie L Lindegaard; Christopher A Wassif; Boris Vaisman; Marcelo Amar; Elizabeth V Wasmuth; Robert Shamburek; Lars B Nielsen; Alan T Remaley; Forbes D Porter
Journal:  Hum Mol Genet       Date:  2008-09-05       Impact factor: 6.150

7.  The liver x receptor in correlation with other nuclear receptors in spontaneous and recurrent abortions.

Authors:  Julia Knabl; Aurelia Pestka; Rebecca Hüttenbrenner; Torsten Plösch; Regina Ensenauer; Lena Welbergen; Stefan Hutter; Maria Günthner-Biller; Udo Jeschke
Journal:  PPAR Res       Date:  2013-04-15       Impact factor: 4.964

Review 8.  Insulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes Mellitus.

Authors:  Luis Sobrevia; Rocío Salsoso; Bárbara Fuenzalida; Eric Barros; Lilian Toledo; Luis Silva; Carolina Pizarro; Mario Subiabre; Roberto Villalobos; Joaquín Araos; Fernando Toledo; Marcelo González; Jaime Gutiérrez; Marcelo Farías; Delia I Chiarello; Fabián Pardo; Andrea Leiva
Journal:  Front Physiol       Date:  2016-03-31       Impact factor: 4.566

Review 9.  Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta.

Authors:  Waranya Chatuphonprasert; Kanokwan Jarukamjorn; Isabella Ellinger
Journal:  Front Pharmacol       Date:  2018-09-12       Impact factor: 5.810

Review 10.  Liver X Receptors: A Possible Link between Lipid Disorders and Female Infertility.

Authors:  Sarah Dallel; Igor Tauveron; Florence Brugnon; Silvère Baron; Jean Marc A Lobaccaro; Salwan Maqdasy
Journal:  Int J Mol Sci       Date:  2018-07-25       Impact factor: 5.923
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