Literature DB >> 15673774

Simple fibroblast-based assay to test the pyrazinamide susceptibility of Mycobacterium tuberculosis.

Takemasa Takii1, Sonomi Hamasaki, Kazue Hirano, Chiyoji Abe, Kikuo Onozaki.   

Abstract

A simple fibroblast-based assay (SFA) was found to be efficient in evaluating the susceptibilities of clinical isolates of Mycobacterium tuberculosis to pyrazinamide (PZA). Forty-five clinical isolates were examined. The MICs of PZA for susceptible strains in an SFA were between 3.13 and 12.5 microg/ml, and the MICs of PZA for resistant strains were more than 100 microg/ml.

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Year:  2005        PMID： 15673774      PMCID： PMC547215          DOI： 10.1128/AAC.49.2.804-807.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

1.  Comparison of the ESP and BACTEC systems for testing susceptibilities of Mycobacterium tuberculosis complex isolates to pyrazinamide.

Authors:  Vincent J LaBombardi
Journal:  J Clin Microbiol       Date:  2002-06       Impact factor: 5.948

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Authors:  R Tummon
Journal:  Med Lab Technol       Date:  1975-07

3.  New agar medium for testing susceptibility of Mycobacterium tuberculosis to pyrazinamide.

Authors:  L Heifets; T Sanchez
Journal:  J Clin Microbiol       Date:  2000-04       Impact factor: 5.948

4.  Pyrazinamide susceptibility and amidase activity of tubercle bacilli.

Authors:  K Konno; F M Feldmann; W McDermott
Journal:  Am Rev Respir Dis       Date:  1967-03

5.  Killing of macrophage-ingested mycobacteria by rifampicin, pyrazinamide, and pyrazinoic acid alone and in combination.

Authors:  N A Carlone; G Acocella; A M Cuffini; M Forno-Pizzoglio
Journal:  Am Rev Respir Dis       Date:  1985-12

6.  The action of antituberculosis drugs in short-course chemotherapy.

Authors:  D A Mitchison
Journal:  Tubercle       Date:  1985-09

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Authors:  L G Wayne
Journal:  Am Rev Respir Dis       Date:  1974-01

8.  Interleukin-1 or tumor necrosis factor-alpha augmented the cytotoxic effect of mycobacteria on human fibroblasts: application to evaluation of pathogenesis of clinical isolates of Mycobacterium tuberculosis and M. avium complex.

Authors:  T Takii; C Abe; A Tamura; S Ramayah; J T Belisle; P J Brennan; K Onozaki
Journal:  J Interferon Cytokine Res       Date:  2001-03       Impact factor: 2.607

9.  Simple fibroblast-based assay for screening of new antimicrobial drugs against Mycobacterium tuberculosis.

Authors:  Takemasa Takii; Yoshifumi Yamamoto; Taku Chiba; Chiyoji Abe; John T Belisle; Patrick J Brennan; Kikuo Onozaki
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

10.  Evaluation of BACTEC MGIT 960 PZA medium for susceptibility testing of Mycobacterium tuberculosis to pyrazinamide (PZA): compared with the results of pyrazinamidase assay and Kyokuto PZA test.

Authors:  Akio Aono; Kazue Hirano; Sonomi Hamasaki; Chiyoji Abe
Journal:  Diagn Microbiol Infect Dis       Date:  2002-12       Impact factor: 2.803
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