Literature DB >> 15673510

Toxigenic status of Clostridium difficile in a large Spanish teaching hospital.

R Alonso1, A Martín1, T Peláez1, M Marín1, M Rodríguez-Creixéms1, E Bouza1.   

Abstract

The aim of this study was to evaluate the toxigenic status of circulating strains of Clostridium difficile in a large teaching hospital. Overall 220 isolates were studied of which 199 (90.5 %) produced both large clostridial toxins detected by conventional methods. Ten more strains (4.5 %) had toxin A and B genes detectable by PCR. Eleven (5.0 %) variant strains (A- B+) were detected among the isolates studied and 10 strains (4.5 %) had the binary toxin genes (cdtA and cdtB).

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Year:  2005        PMID: 15673510     DOI: 10.1099/jmm.0.45809-0

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN: 0022-2615            Impact factor:   2.472


  3 in total

Review 1.  Clostridium difficile binary toxin CDT: mechanism, epidemiology, and potential clinical importance.

Authors:  Dale N Gerding; Stuart Johnson; Maja Rupnik; Klaus Aktories
Journal:  Gut Microbes       Date:  2013-10-31

2.  Prevalence of Clostridium difficile and its toxigenic genotype in beef samples in west of Iran.

Authors:  Malihe Kheradmand; Somayeh Jalilian; Amirhooshang Alvandi; Ramin Abiri
Journal:  Iran J Microbiol       Date:  2017-06

3.  Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.

Authors:  Richard A Stabler; Miao He; Lisa Dawson; Melissa Martin; Esmeralda Valiente; Craig Corton; Trevor D Lawley; Mohammed Sebaihia; Michael A Quail; Graham Rose; Dale N Gerding; Maryse Gibert; Michel R Popoff; Julian Parkhill; Gordon Dougan; Brendan W Wren
Journal:  Genome Biol       Date:  2009-09-25       Impact factor: 13.583

  3 in total

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