| Literature DB >> 15673264 |
Hiroshi Morita1, Nozomi Ishioka, Hiroshi Takatsu, Takakazu Shinzato, Yutaro Obara, Norimichi Nakahata, Jun'ichi Kobayashi.
Abstract
[structure: see text] Two novel alkaloids with an unprecedented fused-pentacyclic skeleton, daphmanidins C (1) and D (2), have been isolated from the leaves of Daphniphyllum teijsmanii, and the structures were elucidated on the basis of spectroscopic data. The relative stereochemistry of 1 and 2 was assigned by combination of NOESY correlations and a simulation analysis. Daphmanidin C (1) elevated activity of NGF biosynthesis.Entities:
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Year: 2005 PMID： 15673264 DOI： 10.1021/ol047641+
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005