Literature DB >> 15673205

High-frequency stimulation of the subthalamic nucleus for the treatment of Parkinson's disease--a team perspective.

Manjit K Sanghera1, J Michael Desaloms, R Malcolm Stewart.   

Abstract

Parkinson's disease (PD) is a debilitating neurodegenerative disorder affecting more than 1.2 million people in the United States. Genetic and environmental toxins are believed to be risk factors in acquiring the disease. PD is characterized by tremors, rigidity, bradykinesia, poor gait, and postural instability. These cardinal symptoms improve with medication such a levo-dopa (L-dopa). However, over time, as the disease progresses, the patient becomes refractory to medication, or medication produces debilitating side effects. When this occurs or when there are worsening of symptoms, neurosurgical treatment is recommended, particularly deep brain stimulating (DBS) electrodes implanted in the subcortical subthalamic nucleus (STN). Over the last 5 years STN DBS has gained acceptance and become the neurosurgical treatment of choice for PD. To achieve maximum beneficial effects with minimum adverse effects from the surgery, the expertise of an integrated team of physicians and nurses is essential. A clear understanding of the different aspects of the procedure, including the risks and benefits of the treatment, assists neuroscience nurses in communicating with the PD patient, and providing the most appropriate, knowledge-based pre- and postoperative care.

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Year:  2004        PMID: 15673205     DOI: 10.1097/01376517-200412000-00003

Source DB:  PubMed          Journal:  J Neurosci Nurs        ISSN: 0888-0395            Impact factor:   1.230


  4 in total

1.  Chronic high-frequency stimulation therapy in hemiparkinsonian rhesus monkeys using an implanted human DBS system.

Authors:  Yiqun Cao; Peihao Yin; Xiaowu Hu; Yiqin Ge; Xiaoping Zhou
Journal:  Neurol Sci       Date:  2012-05-24       Impact factor: 3.307

Review 2.  Stimulating debate: ethics in a multidisciplinary functional neurosurgery committee.

Authors:  Paul J Ford; Cynthia S Kubu
Journal:  J Med Ethics       Date:  2006-02       Impact factor: 2.903

3.  Muscle Contraction as a False Localizing Sign During Intraoperative Macrostimulation of Subthalamic Nucleus.

Authors:  Gian D Pal; Sepehr Sani; Leo Verhagen
Journal:  Mov Disord Clin Pract       Date:  2015-02-24

4.  Bridging the Gaps in Patient Education for DBS Surgery in Parkinson's Disease.

Authors:  Colleen D Knoop; Robert Kadish; Kathy Hager; Michael C Park; Paul D Loprinzi; Kathrin LaFaver
Journal:  Parkinsons Dis       Date:  2017-08-07
  4 in total

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