Submicro scale NMR sample preparation for volatile chemicals.

A simple, inexpensive, and highly efficient NMR sample preparation technique for volatile chemicals has been devised using a micropreparative GC system. The recovery efficiency of a volatile chemical using this technique was >80% with sample sizes of 0.05 to 0.5 microg. The purity of the acquired NMR samples was sufficient for high sensitive NMR analyses including two dimensional experiments.