BACKGROUND: The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel. This study examined the effect of bowel preparation on the volume of intestinal content and on small-bowel transit. METHODS:Sixty-one consecutive patients (34 men, 27 women; mean age 56 years, range 17-88 years) were enrolled in the study. Although not randomized, 33 patients received a bowel preparation, and 28 had no preparation. Gastric emptying, small-bowel transit time, overall preparation assessment, and bowel-wall visualization were evaluated by 3 investigators who were unaware of whether the patient had undergone bowel preparation. RESULTS:Small-bowel transit time was significantly shorter in patients with bowel preparation (median 213 minutes: 95% CI[190, 267]) than in those without preparation (median 253 minutes: 95% CI[228, 307]) (p <0.01). The capsule reached the cecum in 97% of patients in the bowel-preparation group, compared with 76% in the nonpreparation group (p=0.02). Bowel preparation improved the quality of visualization significantly; this effect was more pronounced in the distal small bowel. CONCLUSIONS: This study demonstrated that bowel preparation accelerates small-bowel capsule transit and leads to a higher rate of complete capsule endoscopy. Visualization of the small bowel was improved by bowel preparation. Bowel preparation before capsule endoscopy is recommended.
RCT Entities:
BACKGROUND: The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel. This study examined the effect of bowel preparation on the volume of intestinal content and on small-bowel transit. METHODS: Sixty-one consecutive patients (34 men, 27 women; mean age 56 years, range 17-88 years) were enrolled in the study. Although not randomized, 33 patients received a bowel preparation, and 28 had no preparation. Gastric emptying, small-bowel transit time, overall preparation assessment, and bowel-wall visualization were evaluated by 3 investigators who were unaware of whether the patient had undergone bowel preparation. RESULTS: Small-bowel transit time was significantly shorter in patients with bowel preparation (median 213 minutes: 95% CI[190, 267]) than in those without preparation (median 253 minutes: 95% CI[228, 307]) (p <0.01). The capsule reached the cecum in 97% of patients in the bowel-preparation group, compared with 76% in the nonpreparation group (p=0.02). Bowel preparation improved the quality of visualization significantly; this effect was more pronounced in the distal small bowel. CONCLUSIONS: This study demonstrated that bowel preparation accelerates small-bowel capsule transit and leads to a higher rate of complete capsule endoscopy. Visualization of the small bowel was improved by bowel preparation. Bowel preparation before capsule endoscopy is recommended.
Authors: Alan Barkun; Naoki Chiba; Robert Enns; Margaret Marcon; Susan Natsheh; Co Pham; Dan Sadowski; Stephen Vanner Journal: Can J Gastroenterol Date: 2006-11 Impact factor: 3.522
Authors: Ilja Tachecí; Jaroslav Kvetina; Jan Bures; Jan Osterreicher; Martin Kunes; Jaroslav Pejchal; Stanislav Rejchrt; Stanislav Spelda; Marcela Kopácová Journal: Dig Dis Sci Date: 2009-12-16 Impact factor: 3.199
Authors: Andreas Franke; Frank Hummel; Phillip Knebel; Christoph Antoni; Ulrich Bocker; Manfred V Singer; Matthias Lohr Journal: World J Gastroenterol Date: 2008-04-07 Impact factor: 5.742
Authors: Sung Chul Park; Bora Keum; Jong Jin Hyun; Yeon Seok Seo; Yong Sik Kim; Yoon Tae Jeen; Hoon Jai Chun; Soon Ho Um; Chang Duck Kim; Ho Sang Ryu Journal: World J Gastroenterol Date: 2010-02-21 Impact factor: 5.742
Authors: Bruno Joel Ferreira Rosa; Mara Barbosa; Joana Magalhães; Ana Rebelo; Maria João Moreira; José Cotter Journal: World J Gastrointest Endosc Date: 2013-02-16