Literature DB >> 15671241

Scientific evidence to support a vitamin E and heart disease health claim: research needs.

I Jialal1, S Devaraj.   

Abstract

In addition to epidemiologic studies suggesting a benefit for high intakes of alpha-tocopherol, studies following supplementation in humans have clearly shown that alpha-tocopherol decreases lipid peroxidation, platelet aggregation, and functions as a potent anti-inflammatory agent. However, prospective human clinical trials with alpha-tocopherol alone and in combination with other antioxidants have been largely negative. In this review, we critically appraise the various clinical trials and provide recommendations for future research.

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Year:  2005        PMID: 15671241     DOI: 10.1093/jn/135.2.348

Source DB:  PubMed          Journal:  J Nutr        ISSN: 0022-3166            Impact factor:   4.798


  8 in total

Review 1.  Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.

Authors:  S Saboori; S Shab-Bidar; J R Speakman; E Yousefi Rad; K Djafarian
Journal:  Eur J Clin Nutr       Date:  2015-02-11       Impact factor: 4.016

2.  Genome-wide screening of alpha-tocopherol sensitive genes in heart tissue from alpha-tocopherol transfer protein null mice (ATTP(-/-)).

Authors:  Vihas T Vasu; Brad Hobson; Kishorchandra Gohil; Carroll E Cross
Journal:  FEBS Lett       Date:  2007-03-15       Impact factor: 4.124

3.  Effect of high-dose alpha-tocopherol supplementation on biomarkers of oxidative stress and inflammation and carotid atherosclerosis in patients with coronary artery disease.

Authors:  Sridevi Devaraj; Rong Tang; Beverley Adams-Huet; Andrea Harris; Thanalakshmi Seenivasan; James A de Lemos; Ishwarlal Jialal
Journal:  Am J Clin Nutr       Date:  2007-11       Impact factor: 7.045

4.  Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome.

Authors:  Sridevi Devaraj; Scott Leonard; Maret G Traber; Ishwarlal Jialal
Journal:  Free Radic Biol Med       Date:  2007-12-23       Impact factor: 7.376

Review 5.  Intervention for apoptosis in cardiomyopathy.

Authors:  Hiroyuki Yaoita; Yukio Maruyama
Journal:  Heart Fail Rev       Date:  2008-06       Impact factor: 4.214

6.  Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine.

Authors:  Filipa Ponte; Rosa Sousa; Ana Paula Fernandes; Cristina Gonçalves; José Barbot; Félix Carvalho; Beatriz Porto
Journal:  Orphanet J Rare Dis       Date:  2012-05-16       Impact factor: 4.123

7.  Various Effects of Omega 3 and Omega 3 Plus Vitamin E Supplementations on Serum Glucose Level and Insulin Resistance in Patients with Coronary Artery Disease.

Authors:  Somayeh Saboori; Mahmoud Djalali; Esmaeil Yousefi Rad; Ebrahim Nematipour; Ali Akbar Saboor-Yaraghi; Mohammad Hassan Javanbakht; Mohammad Reza Eshraghian; Atena Ramezani; Fariba Koohdani
Journal:  Iran J Public Health       Date:  2016-11       Impact factor: 1.429

8.  Total Antioxidant Capacity from Dietary Supplement Decreases the Likelihood of Having Metabolic Syndrome in Korean Adults.

Authors:  Subeen Kim; YoonJu Song; Jung Eun Lee; Shinyoung Jun; Sangah Shin; Gyung-Ah Wie; Yoon Hee Cho; Hyojee Joung
Journal:  Nutrients       Date:  2017-09-22       Impact factor: 5.717

  8 in total

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