| Literature DB >> 15671241 |
Abstract
In addition to epidemiologic studies suggesting a benefit for high intakes of alpha-tocopherol, studies following supplementation in humans have clearly shown that alpha-tocopherol decreases lipid peroxidation, platelet aggregation, and functions as a potent anti-inflammatory agent. However, prospective human clinical trials with alpha-tocopherol alone and in combination with other antioxidants have been largely negative. In this review, we critically appraise the various clinical trials and provide recommendations for future research.Entities:
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Year: 2005 PMID: 15671241 DOI: 10.1093/jn/135.2.348
Source DB: PubMed Journal: J Nutr ISSN: 0022-3166 Impact factor: 4.798