Literature DB >> 15668071

Repair of avulsed ventral nerve roots by direct ventral intraspinal implantation after brachial plexus injury.

Henri D Fournier1, Philippe Mercier, Philippe Menei.   

Abstract

Currently, the authors' research confirms that,in humans, communication between the cord and effector muscles can be re-established after multi-ple nerve root avulsion by the implantation of peripheral nerve grafts. Outcomes are still modest,but the possibility of improvement exists. The technique of reimplantation makes it possible to envisage global repair with the possibility of repair of all avulsed regions. The most important factor that could maximize the extent of functional recovery is reducing the time between the injury and corrective surgery: the diagnosis of avulsion within 10 days and reparative surgery within 3 weeks is the objective. This goal will involve a global re-evaluation of how these patients are managed. The problem of the recovery of sensory function (tactile and fine perception and proprioception) warrants further work. It seems likely that methods combining medullary reimplantation with neurotization will be the best way of correcting these lesions of the brachial plexus. In this context, cross-disciplinary collaboration is probably more important than ever. The place that methods based on reimplantation will have in the final picture remains to be seen. The key question is in which patients should medullary reimplantation be attempted and which method should be used. Moreover, medullary reimplantation should be considered as an adjunct to all other surgical options and should not compromise the chance of the latter modalities to be effective.An important point remains: are physicians going to be able to map out all the boundaries of this question in the future?

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Year:  2005        PMID: 15668071     DOI: 10.1016/j.hcl.2004.09.001

Source DB:  PubMed          Journal:  Hand Clin        ISSN: 0749-0712            Impact factor:   1.907


  10 in total

1.  Brachial plexus injury: nerve reconstruction and functioning muscle transplantation.

Authors:  David Chwei-Chin Chuang
Journal:  Semin Plast Surg       Date:  2010-02       Impact factor: 2.314

2.  Microanatomy of the brachial plexus roots and its clinical significance.

Authors:  Li-Yuan Zhong; Ai-Ping Wang; Li Hong; Sheng-Hua Chen; Xian-Qin Wang; Yun-Cheng Lv; Tian-Hong Peng
Journal:  Surg Radiol Anat       Date:  2016-11-19       Impact factor: 1.246

3.  Surgical outcomes following nerve transfers in upper brachial plexus injuries.

Authors:  P S Bhandari; L P Sadhotra; P Bhargava; A S Bath; M K Mukherjee; Tejinder Bhatti; Sanjay Maurya
Journal:  Indian J Plast Surg       Date:  2009-07

4.  Diagnosis and management of adult BPI: Results of first 50 cases.

Authors:  Pawan Agarwal; Saket Mittal; Dhananjaya Sharma
Journal:  J Clin Orthop Trauma       Date:  2020-07-01

5.  Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human.

Authors:  Quan Wen; Huandi Weng; Tao Liu; Lingtai Yu; Tianyun Zhao; Jingwen Qin; Si Li; Qingfeng Wu; Fadel Tissir; Yibo Qu; Libing Zhou
Journal:  Brain       Date:  2022-04-18       Impact factor: 15.255

Review 6.  Multiple uses of fibrin sealant for nervous system treatment following injury and disease.

Authors:  Natalia Perussi Biscola; Luciana Politti Cartarozzi; Suzana Ulian-Benitez; Roberta Barbizan; Mateus Vidigal Castro; Aline Barroso Spejo; Rui Seabra Ferreira; Benedito Barraviera; Alexandre Leite Rodrigues Oliveira
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2017-03-14

7.  Brachial plexus injury in adults: Diagnosis and surgical treatment strategies.

Authors:  Mukund R Thatte; Sonali Babhulkar; Amita Hiremath
Journal:  Ann Indian Acad Neurol       Date:  2013-01       Impact factor: 1.383

8.  Functional motor recovery from motoneuron axotomy is compromised in mice with defective corticospinal projections.

Authors:  Yuetong Ding; Yibo Qu; Jia Feng; Meizhi Wang; Qi Han; Kwok-Fai So; Wutian Wu; Libing Zhou
Journal:  PLoS One       Date:  2014-07-08       Impact factor: 3.240

Review 9.  Magnetic resonance imaging for detecting root avulsions in traumatic adult brachial plexus injuries: protocol for a systematic review of diagnostic accuracy.

Authors:  Ryckie G Wade; Yemisi Takwoingi; Justin C R Wormald; John P Ridgway; Steven Tanner; James J Rankine; Grainne Bourke
Journal:  Syst Rev       Date:  2018-05-19

10.  Diffusion Tensor Imaging for Diagnosing Root Avulsions in Traumatic Adult Brachial Plexus Injuries: A Proof-of-Concept Study.

Authors:  Ryckie G Wade; Steven F Tanner; Irvin Teh; John P Ridgway; David Shelley; Brian Chaka; James J Rankine; Gustav Andersson; Mikael Wiberg; Grainne Bourke
Journal:  Front Surg       Date:  2020-04-16
  10 in total

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