| Literature DB >> 15664818 |
Ronald Palin1, David R Barn, John K Clark, Jean E Cottney, Phillip M Cowley, Marc Crockatt, Louise Evans, Helen Feilden, Richard R Goodwin, Frank Griekspoor, Simon J A Grove, Andrea K Houghton, Philip S Jones, Richard J Morphy, Alasdair R C Smith, Hardy Sundaram, David Vrolijk, Mark A Weston, Grant Wishart, Paul Wren.
Abstract
A series of 3-phenoxypropyl piperidine analogues have been discovered as novel ORL1 receptor agonists. Structure-activity relationships have been explored around the 3-phenoxypropyl region with several potent and selective analogues identified.Entities:
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Year: 2005 PMID： 15664818 DOI： 10.1016/j.bmcl.2004.11.049
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823