| Literature DB >> 15664460 |
An De Naeyer1, Victoria Pocock, Stuart Milligan, Denis De Keukeleire.
Abstract
The estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum and five fractions obtained by solid-phase extraction were investigated using estrogen-responsive bioassays, a yeast cell assay and the Ishikawa Var-I assay. The extract was found to exhibit significant estrogenic activity in both assays. Furthermore, bioassay-guided fractionation led to localisation of the estrogenicity in the relatively non-polar fractions of the polyphenolic extract.Entities:
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Year: 2005 PMID: 15664460 DOI: 10.1016/j.fitote.2004.10.002
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882