Literature DB >> 15664169

The molecular machinery of resurgent sodium current revealed.

Bruce P Bean1.   

Abstract

Some TTX-sensitive sodium channels open transiently during recovery from inactivation, generating a "resurgent" sodium current that flows immediately following action potentials. In this issue of Neuron, Grieco and colleagues present evidence that resurgent sodium current results from a novel form of inactivation in which the cytoplasmic tail of the beta4 subunit acts as a classic open-channel blocker.

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Year:  2005        PMID： 15664169     DOI： 10.1016/j.neuron.2005.01.006

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  8 in total

Review 1.  Ionic channel function in action potential generation: current perspective.

Authors:  Gytis Baranauskas
Journal:  Mol Neurobiol       Date:  2007-04       Impact factor: 5.590

Review 2.  Beyond faithful conduction: short-term dynamics, neuromodulation, and long-term regulation of spike propagation in the axon.

Authors:  Dirk Bucher; Jean-Marc Goaillard
Journal:  Prog Neurobiol       Date:  2011-06-17       Impact factor: 11.685

3.  Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons.

Authors:  Alexandra B Klinger; Mirjam Eberhardt; Andrea S Link; Barbara Namer; Lisa K Kutsche; E Theresa Schuy; Ruth Sittl; Tali Hoffmann; Christian Alzheimer; Tobias Huth; Richard W Carr; Angelika Lampert
Journal:  Mol Pain       Date:  2012-09-15       Impact factor: 3.395

4.  Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.

Authors:  Ging Kuo Wang; Thomas Edrich; Sho-Ya Wang
Journal:  J Gen Physiol       Date:  2006-03       Impact factor: 4.086

Review 5.  A new look at sodium channel β subunits.

Authors:  Sivakumar Namadurai; Nikitha R Yereddi; Fiona S Cusdin; Christopher L H Huang; Dimitri Y Chirgadze; Antony P Jackson
Journal:  Open Biol       Date:  2015-01       Impact factor: 6.411

6.  Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.

Authors:  Jinhong Wie; Apoorva Bharthur; Morgan Wolfgang; Vinodh Narayanan; Keri Ramsey; Kimberly Aranda; Qi Zhang; Yandong Zhou; Dejian Ren
Journal:  Nat Commun       Date:  2020-07-03       Impact factor: 14.919

7.  Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons.

Authors:  Cindy Barbosa; Zhi-Yong Tan; Ruizhong Wang; Wenrui Xie; Judith A Strong; Reesha R Patel; Michael R Vasko; Jun-Ming Zhang; Theodore R Cummins
Journal:  Mol Pain       Date:  2015-09-25       Impact factor: 3.395

8.  The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients.

Authors:  Mariam A Sheilabi; Louise Y Takeshita; Edward J Sims; Francesco Falciani; Alessandra P Princivalle
Journal:  Int J Mol Sci       Date:  2020-04-22       Impact factor: 5.923
  8 in total

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