Literature DB >> 1566373

Src-related protein tyrosine kinases and T-cell receptor signalling.

A Veillette1, D Davidson.   

Abstract

Upon antigen stimulation, the T-cell receptor for antigen transduces an intracellular protein tyrosine phosphorylation signal that is critical for subsequent T-lymphocyte activation. As the antigen receptor does not possess an intrinsic protein tyrosine kinase activity, the mechanism by which it regulates protein tyrosine phosphorylation is unconventional. Evidence is increasing that the Src-related protein tyrosine kinases P56lck and p59fyn, as well as the protein tyrosine phosphatase CD45, are involved in this process.

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Year:  1992        PMID: 1566373     DOI: 10.1016/0168-9525(92)90351-4

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  17 in total

1.  Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production.

Authors:  A J da Silva; Z Li; C de Vera; E Canto; P Findell; C E Rudd
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-08       Impact factor: 11.205

2.  Alzheimer's disease risk factor lymphocyte-specific protein tyrosine kinase regulates long-term synaptic strengthening, spatial learning and memory.

Authors:  Eun-Jung Kim; Francisco J Monje; Lin Li; Harald Höger; Daniela D Pollak; Gert Lubec
Journal:  Cell Mol Life Sci       Date:  2012-09-25       Impact factor: 9.261

3.  Requirement of the SH3 and SH2 domains for the inhibitory function of tyrosine protein kinase p50csk in T lymphocytes.

Authors:  J F Cloutier; L M Chow; A Veillette
Journal:  Mol Cell Biol       Date:  1995-11       Impact factor: 4.272

4.  Two novel transmembrane protein tyrosine kinases expressed during Caenorhabditis elegans hypodermal development.

Authors:  W R Morgan; I Greenwald
Journal:  Mol Cell Biol       Date:  1993-11       Impact factor: 4.272

5.  Oncogene activation of HIV-LTR-driven expression via the NF-kappa B binding sites.

Authors:  J T Bruder; G Heidecker; T H Tan; J C Weske; D Derse; U R Rapp
Journal:  Nucleic Acids Res       Date:  1993-11-11       Impact factor: 16.971

6.  Functional dissection of p56lck, a protein tyrosine kinase which mediates interleukin-2-induced activation of the c-fos gene.

Authors:  H Shibuya; K Kohu; K Yamada; E L Barsoumian; R M Perlmutter; T Taniguchi
Journal:  Mol Cell Biol       Date:  1994-09       Impact factor: 4.272

7.  Solution studies of the SH2 domain from the fyn tyrosine kinase: secondary structure, backbone dynamics and protein association.

Authors:  A Pintar; M Hensmann; K Jumel; M Pitkeathly; S E Harding; I D Campbell
Journal:  Eur Biophys J       Date:  1996       Impact factor: 1.733

8.  Ntk: a Csk-related protein-tyrosine kinase expressed in brain and T lymphocytes.

Authors:  L M Chow; C Jarvis; Q Hu; S H Nye; F G Gervais; A Veillette; L A Matis
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-24       Impact factor: 11.205

9.  Ala-->Gly mutation in the putative catalytic loop confers temperature sensitivity on Ros, insulin receptor, and insulin-like growth factor I receptor protein-tyrosine kinases.

Authors:  J Chen; T Hanafusa; L H Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205

10.  Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.

Authors:  L Caron; N Abraham; T Pawson; A Veillette
Journal:  Mol Cell Biol       Date:  1992-06       Impact factor: 4.272

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