Literature DB >> 15663719

Haemovigilance in a general university hospital: need for a more comprehensive classification and a codification of transfusion-related events.

M A Siegenthaler1, P Schneider, D-H Vu, J-D Tissot.   

Abstract

BACKGROUND AND OBJECTIVES: The purpose of this study was to analyse the transfusion-related events recorded in a general university hospital.
MATERIALS AND METHODS: The method we used was retrospective analysis of the data collected between 1999 and 2003.
RESULTS: The incidence of transfusion reactions (n = 394) was 4.19 per 1000 blood products distributed: 59% (n = 231) were febrile non-haemolytic transfusion reactions; 22% (n = 88) were caused by allergy; 5% (n = 21) were caused by bacterial infection; and 14% (n = 54) were classified as other reactions. Platelet concentrates gave rise to a significantly greater number of reactions than erythrocyte concentrates and fresh-frozen plasma. Transfusion errors and near-miss events were also observed and were analysed separately. A series of transfusion-related events, such as haemosiderosis, metabolic disturbances or volume overload, were not reported.
CONCLUSIONS: Our experience prompts us to propose a more comprehensive classification and codification of transfusion-related events.

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Year:  2005        PMID: 15663719     DOI: 10.1111/j.1423-0410.2005.00559.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


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