Literature DB >> 1566027

[Spinal muscular atrophy in Braunvieh calves].

H Stocker1, P Ossent, R Heckmann, C Oertle.   

Abstract

Clinical, neurophysiological and histopathological findings of sixteen cases of spinal muscular atrophy in calves are described. The first clinical signs usually were noticed at 2-6 weeks of age. The animals showed weakness in the hindquarters, trembling and ultimate recumbency. There was a marked muscular atrophy in all four extremities. In addition, secondary bronchopneumonia was evident in 11 cases. Histopathological lesions consisted of degenerative changes in the neurons of the ventral horns and the axons of the spinal cord as well as degeneration of nerve axons in the extremities. Neurophysiological measurements revealed spontaneous activity in the muscles of the limbs. The conditions is autosomal recessive. So far 11 bulls have been identified and excluded from breeding.

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Year:  1992        PMID: 1566027

Source DB:  PubMed          Journal:  Schweiz Arch Tierheilkd        ISSN: 0036-7281            Impact factor:   0.845


  2 in total

1.  Mapping of the bovine spinal muscular atrophy locus to Chromosome 24.

Authors:  Ivica Medugorac; Juliane Kemter; Ingolf Russ; Detlef Pietrowski; Stefan Nüske; Horst-Dieter Reichenbach; Wolfgang Schmahl; Martin Förster
Journal:  Mamm Genome       Date:  2003-06       Impact factor: 2.957

2.  Spinal Muscular Atrophy in Blonde D'Aquitaine Calves Is Not Associated With FVT1 Gene Mutation.

Authors:  Giulia Cagnotti; Carlo Cantile; Stefania Chessa; Paola Sacchi; Antonio D'Angelo; Claudio Bellino
Journal:  Front Vet Sci       Date:  2020-06-23
  2 in total

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