Literature DB >> 15659376

Specific erythrocyte binding capacity and biological activity of Plasmodium falciparum erythrocyte binding ligand 1 (EBL-1)-derived peptides.

Hernando Curtidor1, Luis E Rodríguez, Marisol Ocampo, Ramses López, Javier E García, John Valbuena, Ricardo Vera, Alvaro Puentes, Magnolia Vanegas, Manuel E Patarroyo.   

Abstract

Erythrocyte binding ligand 1 (EBL-1) is a member of the ebl multigene family involved in Plasmodium falciparum invasion of erythrocytes. We found that five EBL-1 high-activity binding peptides (HABPs) bound specifically to erythrocytes: 29895 ((41)HKKKSGELNNNKSGILRSTY(60)), 29903 ((201)LYECGK-KIKEMKWICTDNQF(220)), 29923 ((601)CNAILGSYADIGDIVRGLDV(620)), 29924((621)WRDINTNKLSEK-FQKIFMGGY(640)), and 30018 ((2481)LEDIINLSKKKKKSINDTSFY(2500)). We also show that binding was saturable, not sialic acid-dependent, and that all peptides specifically bound to a 36-kDa protein on the erythrocyte membrane. The five HABPs inhibited in vitro merozoite invasion depending on the peptide concentration used, suggesting their possible role in the invasion process.

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Year:  2005        PMID： 15659376      PMCID： PMC2254251          DOI： 10.1110/ps.041084305

Source DB:  PubMed          Journal:  Protein Sci        ISSN： 0961-8368            Impact factor:   6.725


  45 in total

1.  Plasmodium falciparum EBA-175 kDa protein peptides which bind to human red blood cells.

Authors:  L E Rodriguez; M Urquiza; M Ocampo; J Suarez; H Curtidor; F Guzman; L E Vargas; M Triviños; M Rosas; M E Patarroyo
Journal:  Parasitology       Date:  2000-03       Impact factor: 3.234

2.  Classification of adhesive domains in the Plasmodium falciparum erythrocyte membrane protein 1 family.

Authors:  J D Smith; G Subramanian; B Gamain; D I Baruch; L H Miller
Journal:  Mol Biochem Parasitol       Date:  2000-10       Impact factor: 1.759

Review 3.  An expanding ebl family of Plasmodium falciparum.

Authors:  J H Adams; P L Blair; O Kaneko; D S Peterson
Journal:  Trends Parasitol       Date:  2001-06

4.  Characterization of a Plasmodium falciparum erythrocyte-binding protein paralogous to EBA-175.

Authors:  D C Mayer; O Kaneko; D E Hudson-Taylor; M E Reid; L H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-17       Impact factor: 11.205

5.  EBL-1, a putative erythrocyte binding protein of Plasmodium falciparum, maps within a favored linkage group in two genetic crosses.

Authors:  D S Peterson; T E Wellems
Journal:  Mol Biochem Parasitol       Date:  2000-01-05       Impact factor: 1.759

6.  Disruption of the C-terminal region of EBA-175 in the Dd2/Nm clone of Plasmodium falciparum does not affect erythrocyte invasion.

Authors:  O Kaneko; D A Fidock; O M Schwartz; L H Miller
Journal:  Mol Biochem Parasitol       Date:  2000-09       Impact factor: 1.759

7.  Antibodies against the Plasmodium falciparum receptor binding domain of EBA-175 block invasion pathways that do not involve sialic acids.

Authors:  D L Narum; J D Haynes; S Fuhrmann; K Moch; H Liang; S L Hoffman; B K Sim
Journal:  Infect Immun       Date:  2000-04       Impact factor: 3.441

Review 8.  Host cell invasion by malaria parasites.

Authors:  C E Chitnis; M J Blackman
Journal:  Parasitol Today       Date:  2000-10

9.  Targeted disruption of an erythrocyte binding antigen in Plasmodium falciparum is associated with a switch toward a sialic acid-independent pathway of invasion.

Authors:  M B Reed; S R Caruana; A H Batchelor; J K Thompson; B S Crabb; A F Cowman
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-20       Impact factor: 11.205

10.  Interaction between cytochalasin B-treated malarial parasites and erythrocytes. Attachment and junction formation.

Authors:  L H Miller; M Aikawa; J G Johnson; T Shiroishi
Journal:  J Exp Med       Date:  1979-01-01       Impact factor: 14.307
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  7 in total

1.  Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells.

Authors:  Xuerong Li; Marina Marinkovic; Crystal Russo; C James McKnight; Theresa L Coetzer; Athar H Chishti
Journal:  Mol Biochem Parasitol       Date:  2012-01-16       Impact factor: 1.759

2.  Identifying putative Mycobacterium tuberculosis Rv2004c protein sequences that bind specifically to U937 macrophages and A549 epithelial cells.

Authors:  Martha Forero; Alvaro Puentes; Jimena Cortés; Fabio Castillo; Ricardo Vera; Luis E Rodríguez; John Valbuena; Marisol Ocampo; Hernando Curtidor; Jaiver Rosas; Javier García; Gloria Barrera; Rosalba Alfonso; Manuel A Patarroyo; Manuel E Patarroyo
Journal:  Protein Sci       Date:  2005-09-30       Impact factor: 6.725

3.  Mycobacterium tuberculosis Rv0679c protein sequences involved in host-cell infection: potential TB vaccine candidate antigen.

Authors:  Diana P Cifuentes; Marisol Ocampo; Hernando Curtidor; Magnolia Vanegas; Martha Forero; Manuel E Patarroyo; Manuel A Patarroyo
Journal:  BMC Microbiol       Date:  2010-04-13       Impact factor: 3.605

4.  Glycophorin B is the erythrocyte receptor of Plasmodium falciparum erythrocyte-binding ligand, EBL-1.

Authors:  D C Ghislaine Mayer; Joann Cofie; Lubin Jiang; Daniel L Hartl; Erin Tracy; Juraj Kabat; Laurence H Mendoza; Louis H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-11       Impact factor: 11.205

Review 5.  Conserved Binding Regions Provide the Clue for Peptide-Based Vaccine Development: A Chemical Perspective.

Authors:  Hernando Curtidor; César Reyes; Adriana Bermúdez; Magnolia Vanegas; Yahson Varela; Manuel E Patarroyo
Journal:  Molecules       Date:  2017-12-12       Impact factor: 4.411

Review 6.  The Cellular and Molecular Interaction Between Erythrocytes and Plasmodium falciparum Merozoites.

Authors:  Jessica Molina-Franky; Manuel Elkin Patarroyo; Markus Kalkum; Manuel Alfonso Patarroyo
Journal:  Front Cell Infect Microbiol       Date:  2022-03-31       Impact factor: 5.293

Review 7.  Strategies for developing multi-epitope, subunit-based, chemically synthesized anti-malarial vaccines.

Authors:  M E Patarroyo; G Cifuentes; A Bermúdez; M A Patarroyo
Journal:  J Cell Mol Med       Date:  2008-10       Impact factor: 5.310
  7 in total

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