Literature DB >> 15655753

Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/E.

Rangsima Lolekha1, Sunee Sirivichayakul, Umaporn Siangphoe, Chitsanu Pancharoen, Suchada Kaewchana, Wichitra Apateerapong, Apicha Mahanontharit, Tawee Chotpitayasunondh, Kiat Ruxrungtham, Praphan Phanuphak, Jintanat Ananworanich.   

Abstract

The prevalence of nucleoside reverse-transcriptase inhibitor (NRTI) mutations was determined among 95 human immunodeficiency virus-infected Thai children who were treated with dual nucleoside reverse-transcriptase inhibitors. Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal.

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Year:  2004        PMID: 15655753     DOI: 10.1086/427026

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  1 in total

1.  Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996-2008).

Authors:  Jorge L Martinez-Cajas; Nitika P Pai; Marina B Klein; Mark A Wainberg
Journal:  J Int AIDS Soc       Date:  2009-06-30       Impact factor: 5.396

  1 in total

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