Literature DB >> 15655704

Nutrient, neural and endocrine control of glucagon-like peptide secretion.

P E Dubé1, P L Brubaker.   

Abstract

The intestinal glucagon-like peptides, GLP-1 and GLP-2, are important regulators of nutrient intake, digestion, absorption and metabolism. Extensive studies have shown that the co-secretion of GLP-1 and GLP-2 is regulated by a variety of dietary nutrient, neural and endocrine inputs. Furthermore, secretion of these peptides is altered in a number of pathological conditions, including type 2 diabetes and obesity. The purpose of this review is to discuss the regulation of GLP-1 and GLP-2 secretion in both health and disease.

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Year:  2004        PMID： 15655704     DOI： 10.1055/s-2004-826159

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN： 0018-5043            Impact factor:   2.936


  22 in total

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