Literature DB >> 15653840

A role for the Wilms' tumor protein WT1 in organ development.

Holger Scholz1, Karin M Kirschner.   

Abstract

Wilms' tumor (nephroblastoma) represents a unique example of an aberrant kidney formation that can result from mutations in a tumor suppressor gene, Wilms' tumor 1 (WT1). Targeted gene inactivation in mice testifies that WT1 is a master switch for the development of the genitourinary system and other organs.

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Year:  2005        PMID： 15653840     DOI： 10.1152/physiol.00048.2004

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  17 in total

Review 1.  Ovarian clear cell adenocarcinoma: a continuing enigma.

Authors:  David S P Tan; Stan Kaye
Journal:  J Clin Pathol       Date:  2006-10-03       Impact factor: 3.411

2.  Effects of WT1 gene downregulation on apoptosis in porcine fetal fibroblasts.

Authors:  Peipei An; Yu Ding; Aibing Wang; Wentao Tan; Fei Gao; Anran Fan; Bo Tang; Xueming Zhang; Ziyi Li
Journal:  In Vitro Cell Dev Biol Anim       Date:  2014-03-21       Impact factor: 2.416

Review 3.  A role of WT1 in cell division and genomic stability.

Authors:  Jayasha Shandilya; Stefan G E Roberts
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

4.  HtrA2, taming the oncogenic activities of WT1.

Authors:  Jörg Hartkamp; Stefan G E Roberts
Journal:  Cell Cycle       Date:  2010-07-01       Impact factor: 4.534

5.  WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma.

Authors:  Santiago Saavedra-Alonso; Pablo Zapata-Benavides; Ana Karina Chavez-Escamilla; Edgar Manilla-Muñoz; Diana Elisa Zamora-Avila; Moisés Armides Franco-Molina; Cristina Rodriguez-Padilla
Journal:  Exp Ther Med       Date:  2016-10-27       Impact factor: 2.447

Review 6.  The podocyte as a target: cyclosporin A in the management of the nephrotic syndrome caused by WT1 mutations.

Authors:  Constantinos J Stefanidis; Uwe Querfeld
Journal:  Eur J Pediatr       Date:  2011-02-08       Impact factor: 3.183

7.  Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.

Authors:  Zhenglong Guo; Mengyuan Geng; Yuting Huang; Gang Han; Renwei Jing; Caorui Lin; Xiaoning Zhang; Miaomiao Zhang; Guanwei Fan; Feng Wang; HaiFang Yin
Journal:  Cell Death Differ       Date:  2022-03-19       Impact factor: 12.067

8.  Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation.

Authors:  Kymora B Scotland; Siming Chen; Renia Sylvester; Lorraine J Gudas
Journal:  Dev Dyn       Date:  2009-08       Impact factor: 3.780

Review 9.  Mechanisms of transcriptional regulation by WT1 (Wilms' tumour 1).

Authors:  Eneda Toska; Stefan G E Roberts
Journal:  Biochem J       Date:  2014-07-01       Impact factor: 3.857

10.  Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation.

Authors:  Laura M Green; Kate J Wagner; Hayley A Campbell; Kelly Addison; Stefan G E Roberts
Journal:  Nucleic Acids Res       Date:  2008-12-02       Impact factor: 16.971
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