Literature DB >> 15653269

A family-based study of the association between the G72/G30 genes and schizophrenia in the Chinese population.

Fanggeng Zou1, Chao Li, Shiwei Duan, Yonglan Zheng, Niufan Gu, Guoyin Feng, Yangling Xing, Jianguo Shi, Lin He.   

Abstract

Studies have shown a strong positive association between schizophrenia and G72/G30, demonstrated by both individual markers and haplotypes. A further functional study also supports the role of G72 in the etiology of schizophrenia. In this study, we have replicated these results of transmission/disequilibrium testing (TDT) and haplotype analysis in the Han Chinese population, showing P values of 0.0018 and 0.00007 for individual markers and haplotypes, respectively. Hence, our data supports the hypothesis that G72/G30 are important candidate genes for explaining schizophrenia in the Han Chinese population.

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Year:  2005        PMID: 15653269     DOI: 10.1016/j.schres.2004.01.015

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  13 in total

Review 1.  The G72/G30 gene locus in psychiatric disorders: a challenge to diagnostic boundaries?

Authors:  Rami Abou Jamra; Christine Schmael; Sven Cichon; Marcella Rietschel; Johannes Schumacher; Markus M Nöthen
Journal:  Schizophr Bull       Date:  2006-08-16       Impact factor: 9.306

2.  G72/G30 genes and schizophrenia: a systematic meta-analysis of association studies.

Authors:  Dawei Li; Lin He
Journal:  Genetics       Date:  2006-12-18       Impact factor: 4.562

3.  Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia.

Authors:  Kristin K Nicodemus; Bhaskar S Kolachana; Radhakrishna Vakkalanka; Richard E Straub; Ina Giegling; Michael F Egan; Dan Rujescu; Daniel R Weinberger
Journal:  Hum Genet       Date:  2006-09-28       Impact factor: 4.132

4.  Effect of D-amino acid oxidase activator (DAOA; G72) on brain function during verbal fluency.

Authors:  Diana P Prata; Sergio A Papagni; Andrea Mechelli; Cynthia H Y Fu; Joseph Kambeitz; Marco Picchioni; Fergus Kane; Sridevi Kalidindi; Colm McDonald; Eugenia Kravariti; Timothea Toulopoulou; Elvira Bramon; Muriel Walshe; Robin Murray; David A Collier; Philip K McGuire
Journal:  Hum Brain Mapp       Date:  2011-03-09       Impact factor: 5.038

5.  G72 influences longitudinal change in frontal lobe volume in schizophrenia.

Authors:  Sarah M Hartz; Beng-Choon Ho; Nancy C Andreasen; Amy Librant; Danielle Rudd; Eric A Epping; Thomas H Wassink
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2010-03-05       Impact factor: 3.568

6.  Allelic association of G72/G30 with schizophrenia and bipolar disorder: a comprehensive meta-analysis.

Authors:  Jiajun Shi; Judith A Badner; Elliot S Gershon; Chunyu Liu
Journal:  Schizophr Res       Date:  2007-11-26       Impact factor: 4.939

7.  Genetic variation in the DAOA gene complex: impact on susceptibility for schizophrenia and on cognitive performance.

Authors:  Carolin Opgen-Rhein; Todd Lencz; Katherine E Burdick; Andres H Neuhaus; Pamela DeRosse; Terry E Goldberg; Anil K Malhotra
Journal:  Schizophr Res       Date:  2008-06-09       Impact factor: 4.939

8.  Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia: further evidence for a role in schizophrenia.

Authors:  Takahiro Shinkai; Vincenzo De Luca; Rudi Hwang; Daniel J Müller; Matthew Lanktree; Gwyneth Zai; Sajid Shaikh; Gregory Wong; Tricia Sicard; Natalia Potapova; Joseph Trakalo; Nicole King; Chima Matsumoto; Hiroko Hori; Albert H C Wong; Osamu Ohmori; Fabio Macciardi; Jun Nakamura; James L Kennedy
Journal:  Neuromolecular Med       Date:  2007       Impact factor: 3.843

Review 9.  Genetic bases for endophenotypes in psychiatric disorders.

Authors:  Wade H Berrettini
Journal:  Dialogues Clin Neurosci       Date:  2005       Impact factor: 5.986

10.  Meta-analysis in psychiatric genetics.

Authors:  Douglas F Levinson
Journal:  Curr Psychiatry Rep       Date:  2005-04       Impact factor: 8.081

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