Literature DB >> 15652976

The Icm/Dot type-IV secretion systems of Legionella pneumophila and Coxiella burnetii.

Gil Segal1, Michal Feldman, Tal Zusman.   

Abstract

Type-IV secretion systems are devices present in a wide range of bacteria (including bacterial pathogens) that deliver macromolecules (proteins and single-strand-DNA) across kingdom barriers (as well as between bacteria and into the surroundings). The type-IV secretion systems were divided into two subgroups and Legionella pneumophila and Coxiella burnetii are the only two bacteria known today to utilize a type-IVB secretion system for pathogenesis. In this review we summarized the available information concerning the icm/dot type-IVB secretion systems by comparing the two bacteria that possess this system, the proteins components of their systems as well as the homology of proteins from type-IVB secretion systems to proteins from type-IVA secretion systems. In addition, the phenotypes associated with mutants in the L. pneumophila icm/dot genes, their relations to properties of specific Icm/Dot proteins as well as the protein substrates delivered by this system are described.

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Year:  2005        PMID： 15652976     DOI： 10.1016/j.femsre.2004.07.001

Source DB:  PubMed          Journal:  FEMS Microbiol Rev        ISSN： 0168-6445            Impact factor:   16.408


  97 in total

1.  Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems.

Authors:  Eric Durand; Abdelrahim Zoued; Silvia Spinelli; Paul J H Watson; Marie-Stéphanie Aschtgen; Laure Journet; Christian Cambillau; Eric Cascales
Journal:  J Biol Chem       Date:  2012-02-27       Impact factor: 5.157

Review 2.  Computational prediction of type III and IV secreted effectors in gram-negative bacteria.

Authors:  Jason E McDermott; Abigail Corrigan; Elena Peterson; Christopher Oehmen; George Niemann; Eric D Cambronne; Danna Sharp; Joshua N Adkins; Ram Samudrala; Fred Heffron
Journal:  Infect Immun       Date:  2010-10-25       Impact factor: 3.441

Review 3.  Principles of antidote pharmacology: an update on prophylaxis, post-exposure treatment recommendations and research initiatives for biological agents.

Authors:  S Ramasamy; C Q Liu; H Tran; A Gubala; P Gauci; J McAllister; T Vo
Journal:  Br J Pharmacol       Date:  2010-10       Impact factor: 8.739

4.  Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires.

Authors:  David Burstein; Francisco Amaro; Tal Zusman; Ziv Lifshitz; Ofir Cohen; Jack A Gilbert; Tal Pupko; Howard A Shuman; Gil Segal
Journal:  Nat Genet       Date:  2016-01-11       Impact factor: 38.330

Review 5.  Biogenesis, architecture, and function of bacterial type IV secretion systems.

Authors:  Peter J Christie; Krishnamohan Atmakuri; Vidhya Krishnamoorthy; Simon Jakubowski; Eric Cascales
Journal:  Annu Rev Microbiol       Date:  2005       Impact factor: 15.500

6.  Coevolution between nonhomologous but functionally similar proteins and their conserved partners in the Legionella pathogenesis system.

Authors:  Michal Feldman; Tal Zusman; Shelly Hagag; Gil Segal
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-09       Impact factor: 11.205

7.  Living with genome instability: the adaptation of phytoplasmas to diverse environments of their insect and plant hosts.

Authors:  Xiaodong Bai; Jianhua Zhang; Adam Ewing; Sally A Miller; Agnes Jancso Radek; Dmitriy V Shevchenko; Kiryl Tsukerman; Theresa Walunas; Alla Lapidus; John W Campbell; Saskia A Hogenhout
Journal:  J Bacteriol       Date:  2006-05       Impact factor: 3.490

8.  The global regulatory proteins LetA and RpoS control phospholipase A, lysophospholipase A, acyltransferase, and other hydrolytic activities of Legionella pneumophila JR32.

Authors:  Markus Broich; Kerstin Rydzewski; Tamara L McNealy; Reinhard Marre; Antje Flieger
Journal:  J Bacteriol       Date:  2006-02       Impact factor: 3.490

9.  Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal.

Authors:  Ziv Lifshitz; David Burstein; Michael Peeri; Tal Zusman; Kierstyn Schwartz; Howard A Shuman; Tal Pupko; Gil Segal
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-04       Impact factor: 11.205

Review 10.  Functional diversity of ankyrin repeats in microbial proteins.

Authors:  Souhaila Al-Khodor; Christopher T Price; Awdhesh Kalia; Yousef Abu Kwaik
Journal:  Trends Microbiol       Date:  2009-12-03       Impact factor: 17.079
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