| Literature DB >> 15652671 |
Derek Weycker1, John Edelsberg, M Elizabeth Halloran, Ira M Longini, Azhar Nizam, Vincent Ciuryla, Gerry Oster.
Abstract
Using a stochastic simulation model of influenza transmission, clinical illness, and economic costs, we estimated the population-wide benefits of routinely vaccinating US children (ages 6 months to 18 years) against influenza. Disease burden was projected to decline as a result of both reduced susceptibility to infection among vaccinees and reductions in disease transmission to others in the community. Vaccination of 20% of children would reduce the total number of influenza cases in the US by 46%; 80% coverage would reduce the total number of cases by 91%. Similar reductions were estimated to occur in influenza-related mortality and economic costs.Entities:
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Year: 2005 PMID： 15652671 DOI： 10.1016/j.vaccine.2004.08.044
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641