Literature DB >> 15650222

Vaccination with an inactivated virulent feline immunodeficiency virus engineered to express high levels of Env.

Margaret J Hosie1, Dieter Klein, James M Binley, Thomas H Dunsford, Oswald Jarrett, James C Neil, Elzbieta Knapp, Simone Giannecchini, Donatella Matteucci, Mauro Bendinelli, James A Hoxie, Brian J Willett.   

Abstract

An inactivated virus vaccine was prepared from a pathogenic isolate of feline immunodeficiency virus containing a mutation that eliminated an endocytic sorting signal in the envelope glycoprotein, increasing its expression on virions. Cats immunized with inactivated preparations of this modified virus exhibited strong titers of antibody to Env by enzyme-linked immunosorbent assay. Evidence of protection following challenge demonstrated the potential of this approach to lentiviral vaccination.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15650222      PMCID： PMC544106          DOI： 10.1128/JVI.79.3.1954-1957.2005

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  AIDS vaccination studies using an ex vivo feline immunodeficiency virus model: reevaluation of neutralizing antibody levels elicited by a protective and a nonprotective vaccine after removal of antisubstrate cell antibodies.

Authors:  S Giannecchini; D Del Mauro; D Matteucci; M Bendinelli
Journal:  J Virol       Date:  2001-05       Impact factor: 5.103

2.  Roles for endocytosis in lentiviral replication.

Authors:  M Marsh; A Pelchen-Matthews; J A Hoxie
Journal:  Trends Cell Biol       Date:  1997-01       Impact factor: 20.808

3.  Real time quantitative PCR.

Authors:  C A Heid; J Stevens; K J Livak; P M Williams
Journal:  Genome Res       Date:  1996-10       Impact factor: 9.043

4.  Common mechanism of infection by lentiviruses.

Authors:  B J Willett; M J Hosie; J C Neil; J D Turner; J A Hoxie
Journal:  Nature       Date:  1997-02-13       Impact factor: 49.962

Review 5.  FIV infection of the domestic cat: an animal model for AIDS.

Authors:  B J Willett; J N Flynn; M J Hosie
Journal:  Immunol Today       Date:  1997-04

6.  A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure.

Authors:  J M Binley; R W Sanders; B Clas; N Schuelke; A Master; Y Guo; F Kajumo; D J Anselma; P J Maddon; W C Olson; J P Moore
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

7.  Productive infection of T-helper lymphocytes with feline immunodeficiency virus is accompanied by reduced expression of CD4.

Authors:  B J Willett; M J Hosie; T H Dunsford; J C Neil; O Jarrett
Journal:  AIDS       Date:  1991-12       Impact factor: 4.177

8.  Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1.

Authors:  J M Binley; P J Klasse; Y Cao; I Jones; M Markowitz; D D Ho; J P Moore
Journal:  J Virol       Date:  1997-04       Impact factor: 5.103

9.  A membrane-proximal tyrosine-based signal mediates internalization of the HIV-1 envelope glycoprotein via interaction with the AP-2 clathrin adaptor.

Authors:  M Boge; S Wyss; J S Bonifacino; M Thali
Journal:  J Biol Chem       Date:  1998-06-19       Impact factor: 5.157

10.  An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.

Authors:  M M Sauter; A Pelchen-Matthews; R Bron; M Marsh; C C LaBranche; P J Vance; J Romano; B S Haggarty; T K Hart; W M Lee; J A Hoxie
Journal:  J Cell Biol       Date:  1996-03       Impact factor: 10.539
View more
  5 in total

Review 1.  Advances in FIV vaccine technology.

Authors:  Elizabeth W Uhl; Marcus Martin; James K Coleman; Janet K Yamamoto
Journal:  Vet Immunol Immunopathol       Date:  2008-01-20       Impact factor: 2.046

Review 2.  Feline immunodeficiency virus model for designing HIV/AIDS vaccines.

Authors:  Janet K Yamamoto; Missa P Sanou; Jeffrey R Abbott; James K Coleman
Journal:  Curr HIV Res       Date:  2010-01       Impact factor: 1.581

3.  Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation.

Authors:  James H Morrison; Rebekah B Guevara; Adriana C Marcano; Dyana T Saenz; Hind J Fadel; Daniel K Rogstad; Eric M Poeschla
Journal:  J Virol       Date:  2014-01-03       Impact factor: 5.103

4.  Env-expressing autologous T lymphocytes induce neutralizing antibody and afford marked protection against feline immunodeficiency virus.

Authors:  Mauro Pistello; Francesca Bonci; Elisa Zabogli; Francesca Conti; Giulia Freer; Fabrizio Maggi; Mario Stevenson; Mauro Bendinelli
Journal:  J Virol       Date:  2010-02-03       Impact factor: 5.103

Review 5.  Feline immunodeficiency virus (FIV) neutralization: a review.

Authors:  Margaret J Hosie; Daniela Pajek; Ayman Samman; Brian J Willett
Journal:  Viruses       Date:  2011-10-13       Impact factor: 5.048
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.