[Pharmacogenetics: Important aspects for dermatology].

Pharmacogenetics, pharmacogenomics or metabonomics are terms reflecting a new trend in pharmacology taking into consideration individual factors which influence the effects of drugs. Examples in dermatology include glucose-6-phosphate dehydrogenase-polymorphism (DADPS), dihydropyrimidine dehydrogenase-deficiency (5-Fluoruracil), thiopurine-S-methyltransferase-deficiency (azathioprine), cytochrome P450 isoenzymes and transferases (drug allergy and allergic contact dermatitis), and intolerant reactions to NSAIDs.