Literature DB >> 1564502

Hither neurology: research.

C P Warlow1.   

Abstract

Neurological disability may be prevented, or it may be alleviated if prevention is impossible or ineffective. Research into prevention and alleviation can be "laboratory" or "clinical", the latter being no less scientific than the former. All proposed treatments must be properly evaluated to ensure that effective interventions are widely adopted and ineffective ones abandoned. Unless an intervention has a major effect on outcome (which most do not), the most efficient assessment is by random allocation of patients to the new intervention versus the old. Although there were, and still are, forces opposed to the proper evaluation of treatment, there are strong economic clinical arguments in its favour, which will lead to appropriate targeting of scarce health resources.

Entities:  

Mesh:

Year:  1992        PMID: 1564502      PMCID: PMC1087973          DOI: 10.1136/jnnp.55.suppl.26

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  6 in total

1.  Are clinical trials a cost-effective investment?

Authors:  A S Detsky
Journal:  JAMA       Date:  1989-10-06       Impact factor: 56.272

Review 2.  Antifibrinolytic agents in subarachnoid haemorrhage.

Authors:  K W Lindsay
Journal:  J Neurol       Date:  1987-01       Impact factor: 4.849

3.  Hyperbaric oxygen and multiple sclerosis: final results of a placebo-controlled, double-blind trial.

Authors:  M P Barnes; D Bates; N E Cartlidge; J M French; D A Shaw
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-11       Impact factor: 10.154

4.  All change for research.

Authors:  R Smith
Journal:  Br Med J (Clin Res Ed)       Date:  1987-11-07

5.  The effect of a visit to a neurological clinic upon patients with tension headache.

Authors:  J L Grove; P Butler; P A Millac
Journal:  Practitioner       Date:  1980-02

6.  Referrals to neurologists for headaches not due to structural disease.

Authors:  R Fitzpatrick; A Hopkins
Journal:  J Neurol Neurosurg Psychiatry       Date:  1981-12       Impact factor: 10.154

  6 in total
  1 in total

1.  Threats to academic neurosurgery in the United Kingdom: a personal view.

Authors:  J D Pickard
Journal:  J Neurol Neurosurg Psychiatry       Date:  1993-11       Impact factor: 10.154

  1 in total

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