CosmoDerm/CosmoPlast (human bioengineered collagen) for the aging face.

Type 1 collagen loss in the dermis is one of the primary causes of wrinkles seen in aged skin. Dermal fillers using type 1 collagen derived from bioengineered skin are now being used to treat facial wrinkles. These fillers, known by the trade names of CosmoDerm and CosmoPlast, can be used alone or in combination with hyaluronic acid fillers. The benefit of collagen-based dermal fillers is decreased downtime, decreased bruising, decreased pain on injection, and the ability to return lost structural components to aged skin. Many aesthetic physicians are beginning to use collagen- and hyaluronic-containing fillers in combination to replace both of these natural components of the skin that are lost during the aging process.