Literature DB >> 15643241

Early release of the neurovascular bundles and optical loupe magnification lead to improved and earlier return of potency following radical retropubic prostatectomy.

Marc S Chuang1, R Corey O'Connor, Brett A Laven, Marcelo A Orvieto, Charles B Brendler.   

Abstract

PURPOSE: Since 1999 we have made 2 modifications in the nerve sparing approach to radical retropubic prostatectomy (RRP), namely early release of the neurovascular bundles (NVBs) before division of the posterior membranous urethra and the use of 2.5x optical loupe magnification during NVB preservation. We retrospectively reviewed our results.
MATERIALS AND METHODS: Between January 1998 and August 2003, 507 men underwent RRP for prostate cancer. All surgeries were performed by a single surgeon (CBB). Bilateral nerve sparing procedures were performed in 313 men. Modifications were introduced sequentially to the surgical technique and potency rates were compared to those of patients operated on before these modifications. Patients were divided into groups based on the technique of nerve sparing as group 1 (standard release of the NVB), group 2 (early release of the NVB) and group 3 (early release with loupe magnification). All patients were followed for a minimum of 5 months. Postoperative potency rates were compared among the 3 groups.
RESULTS: Mean followup was 15.9 months. Mean patient age was 56.2 years. The overall potency rate among groups 1, 2 and 3 was 40.5%, 54.8% and 66.1%, respectively. Mean time to potency was 10.7, 8.5 and 2.0 months, respectively. Significant differences were found in the overall potency rate among all groups (p <0.05). Mean time to potency was significantly improved between groups 1 and 3 (p <0.05) and between groups 2 and 3 (p <0.05).
CONCLUSIONS: Minor modifications in nerve sparing technique lead to improved postoperative potency rates and decreased time to potency in men undergoing RRP.

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Year:  2005        PMID: 15643241     DOI: 10.1097/01.ju.0000148941.57203.ec

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  5 in total

1.  Penile rehabilitation following treatment for prostate cancer: an analysis of the current state of the art.

Authors:  Tariq Al Shaiji; Trustin Domes; Gerald Brock
Journal:  Can Urol Assoc J       Date:  2009-02       Impact factor: 1.862

2.  How do you tell whether a change in surgical technique leads to a change in outcome?

Authors:  Andrew J Vickers; Angel M Cronin; Timothy A Masterson; James A Eastham
Journal:  J Urol       Date:  2010-02-20       Impact factor: 7.450

3.  Modified technique for neurovascular bundle preservation during radical prostatectomy: association between technique and recovery of erectile function.

Authors:  Timothy A Masterson; Angel M Serio; John P Mulhall; Andrew J Vickers; James A Eastham
Journal:  BJU Int       Date:  2008-02-15       Impact factor: 5.588

Review 4.  Advances in the study of the peripheral nervous system for erection in animals and humans.

Authors:  Shin-Ichi Hisasue
Journal:  Reprod Med Biol       Date:  2011-05-03

5.  Prospective comparison of one year follow-up outcomes for the open complete intrafascial retropubic versus interfascial nerve-sparing radical prostatectomy.

Authors:  Wael Y Khoder; Raphaela Waidelich; Alexander Buchner; Armin J Becker; Christian G Stief
Journal:  Springerplus       Date:  2014-07-01
  5 in total

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