Literature DB >> 15642683

Aberrant expression of platelet-derived growth factor (PDGF) and PDGF receptor-alpha is associated with advanced bone marrow fibrosis in idiopathic myelofibrosis.

Oliver Bock, Gero Loch, Guntram Büsche, Reinhard von Wasielewski, Jerome Schlué, Hans Kreipe.   

Abstract

The expression of members of the platelet-derived growth factor (PDGF) system in bone marrow cells derived from Idiopathic myelofibrosis (IMF) has been investigated by real-time RT-PCR. Increased expression of PDGFs and the corresponding PDGF receptor a could be demonstrated to be a feature of advanced fibrosis in IMF that is not demonstrable in the prefibrotic phase of the disease.

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Year:  2005        PMID： 15642683

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  13 in total

1.  Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.

Authors:  Simona Stivala; Tamara Codilupi; Sime Brkic; Anne Baerenwaldt; Nilabh Ghosh; Hui Hao-Shen; Stephan Dirnhofer; Matthias S Dettmer; Cedric Simillion; Beat A Kaufmann; Sophia Chiu; Matthew Keller; Maria Kleppe; Morgane Hilpert; Andreas S Buser; Jakob R Passweg; Thomas Radimerski; Radek C Skoda; Ross L Levine; Sara C Meyer
Journal:  J Clin Invest       Date:  2019-03-04       Impact factor: 14.808

2.  Platelet-derived growth factors and their receptors in normal and malignant hematopoiesis.

Authors:  Jean-Baptiste Demoulin; Carmen P Montano-Almendras
Journal:  Am J Blood Res       Date:  2012-01-01

3.  Busy signal: platelet-derived growth factor activation in myelofibrosis.

Authors:  Anna E Marneth; Ann Mullally
Journal:  Haematologica       Date:  2020-08       Impact factor: 9.941

Review 4.  The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control.

Authors:  Alessandro Malara; Vittorio Abbonante; Christian A Di Buduo; Lorenzo Tozzi; Manuela Currao; Alessandra Balduini
Journal:  Cell Mol Life Sci       Date:  2015-01-09       Impact factor: 9.261

5.  Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis.

Authors:  Stefan O Ciurea; Delwin Merchant; Nadim Mahmud; Takefumi Ishii; Yan Zhao; Wenyang Hu; Edward Bruno; Giovanni Barosi; Mingjiang Xu; Ronald Hoffman
Journal:  Blood       Date:  2007-05-01       Impact factor: 22.113

Review 6.  The role of extracellular matrix stiffness in megakaryocyte and platelet development and function.

Authors:  Orly Leiva; Catherine Leon; Seng Kah Ng; Pierre Mangin; Christian Gachet; Katya Ravid
Journal:  Am J Hematol       Date:  2018-01-12       Impact factor: 10.047

7.  HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis.

Authors:  Margaux Sevin; Lucia Kubovcakova; Nicolas Pernet; Sébastien Causse; Franck Vitte; Jean Luc Villeval; Catherine Lacout; Marine Cordonnier; Fernando Rodrigues-Lima; Gaétan Chanteloup; Matthieu Mosca; Marie-Lorraine Chrétien; Jean Noël Bastie; Sylvain Audia; Paul Sagot; Selim Ramla; Laurent Martin; Martin Gleave; Valérie Mezger; Radek Skoda; Isabelle Plo; Carmen Garrido; François Girodon; Aurélie de Thonel
Journal:  Nat Commun       Date:  2018-04-12       Impact factor: 14.919

8.  Myelofibrosis: molecular and cell biological aspects.

Authors:  Hans Kreipe; Guntram Büsche; Oliver Bock; Kais Hussein
Journal:  Fibrogenesis Tissue Repair       Date:  2012-06-06

Review 9.  Circulating Cytokine Levels as Markers of Inflammation in Philadelphia Negative Myeloproliferative Neoplasms: Diagnostic and Prognostic Interest.

Authors:  Julie Mondet; Kais Hussein; Pascal Mossuz
Journal:  Mediators Inflamm       Date:  2015-10-07       Impact factor: 4.711

Review 10.  Cytokine Regulation of Microenvironmental Cells in Myeloproliferative Neoplasms.

Authors:  Gregor Hoermann; Georg Greiner; Peter Valent
Journal:  Mediators Inflamm       Date:  2015-10-12       Impact factor: 4.711
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