OBJECTIVE: The objective of the present retrospective research is to examine cases of verrucous carcinoma of the penis, an uncommon variant of squamous cell carcinoma, as well as to examine the localisation, evolvement and the ways of treatment. METHODS: Patients, treated for carcinoma of the penis at the Clinic of Urology, have been examined for a 13-year interval. From 80 cases of cancer localized in the penis, in only 3 of these verrucous carcinoma has been histologically proved, accounting for 2.4 per cent of the penile cancers. A rare case of a hybrid tumor between verrucous carcinoma and invasive squamous cell carcinoma, which is compared to similar finding as described by other authors. RESULTS: Slow and continuous evolvement of the disease has been observed, which has been followed by periods of aggressive development. The average age of the patients has been specified to be 52.7 years. The tumor has been mainly localized on the surface of the Glans penis. The results have been compared to those described in the literature. CONCLUSION: Wide surgical excision, usually requiring partial or total penectomy, is the treatment of choice. Radiotherapy and chemotherapy have proved to be unsuccessful.
OBJECTIVE: The objective of the present retrospective research is to examine cases of verrucous carcinoma of the penis, an uncommon variant of squamous cell carcinoma, as well as to examine the localisation, evolvement and the ways of treatment. METHODS:Patients, treated for carcinoma of the penis at the Clinic of Urology, have been examined for a 13-year interval. From 80 cases of cancer localized in the penis, in only 3 of these verrucous carcinoma has been histologically proved, accounting for 2.4 per cent of the penile cancers. A rare case of a hybrid tumor between verrucous carcinoma and invasive squamous cell carcinoma, which is compared to similar finding as described by other authors. RESULTS: Slow and continuous evolvement of the disease has been observed, which has been followed by periods of aggressive development. The average age of the patients has been specified to be 52.7 years. The tumor has been mainly localized on the surface of the Glans penis. The results have been compared to those described in the literature. CONCLUSION: Wide surgical excision, usually requiring partial or total penectomy, is the treatment of choice. Radiotherapy and chemotherapy have proved to be unsuccessful.