Literature DB >> 15641087

Evidence for two phenotypes in the metabolism of methotrexate to 7-hydroxymethotrexate in patients with rheumatoid arthritis.

Joseph E Baggott1, S Louis Bridges, Sarah L Morgan.   

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Year:  2005        PMID： 15641087     DOI： 10.1002/art.20742

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


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  4 in total

1.  Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.

Authors:  L B Hughes; T M Beasley; H Patel; H K Tiwari; S L Morgan; J E Baggott; K G Saag; J McNicholl; L W Moreland; G S Alarcón; S L Bridges
Journal:  Ann Rheum Dis       Date:  2006-01-26       Impact factor: 19.103

2.  High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients.

Authors:  Laila Holmboe; Anders M Andersen; Lars Mørkrid; Lars Slørdal; Kirsten Sundby Hall
Journal:  Br J Clin Pharmacol       Date:  2012-01       Impact factor: 4.335

3.  Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation.

Authors:  Joseph E Baggott; Sarah L Morgan
Journal:  Arthritis Rheum       Date:  2009-08

4.  Genetic variants associated with methotrexate efficacy and toxicity in early rheumatoid arthritis: results from the treatment of early aggressive rheumatoid arthritis trial.

Authors:  S Aslibekyan; E E Brown; R J Reynolds; D T Redden; S Morgan; J E Baggott; J Sha; L W Moreland; J R O'Dell; J R Curtis; T R Mikuls; S L Bridges; D K Arnett
Journal:  Pharmacogenomics J       Date:  2013-04-02       Impact factor: 3.550
  4 in total

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