BACKGROUND: The contribution of familial factors to adiposity in children is poorly understood. OBJECTIVE: The objective was to assess differences in growth in the first 6 y of life in children born to either overweight or lean mothers. DESIGN: The body size and composition of 33 children at high risk and 37 children at low risk of obesity on the basis of the mother's overweight [body mass index (BMI; in kg/m(2)) of 30.2 +/- 4.2 and 19.5 +/- 1.1, respectively] were measured repeatedly from 3 mo to 6 y of age at the Children's Hospital of Philadelphia. RESULTS: At year 2, no significant differences in any measure were observed between the high- and low-risk groups. By year 4, weight, BMI, and lean body mass were greater in the high-risk than in the low-risk children. By year 6, weight was even greater in the high-risk than in the low-risk children (23.4 +/- 6.4 compared with 20.4 +/- 2.1 kg; P < 0.02), and, for the first time, fat mass was greater in the high-risk than in the low-risk children (6.7 +/- 5.7 compared with 3.8 +/- 1.2 kg; P < 0.02). Ten of 33 high-risk children exceeded the 85th percentile of BMI at year 6 compared with 1 of 37 low-risk children (odds ratio = 15.7). Accelerated weight gain was predicted by high-risk group status, greater weight at year 2, and lower family income. CONCLUSION: Anthropometric measures were not significantly different between groups at year 2; weight and lean body mass were greater at years 4 and 6, and fat mass was greater at year 6 in high-risk children.
BACKGROUND: The contribution of familial factors to adiposity in children is poorly understood. OBJECTIVE: The objective was to assess differences in growth in the first 6 y of life in children born to either overweight or lean mothers. DESIGN: The body size and composition of 33 children at high risk and 37 children at low risk of obesity on the basis of the mother's overweight [body mass index (BMI; in kg/m(2)) of 30.2 +/- 4.2 and 19.5 +/- 1.1, respectively] were measured repeatedly from 3 mo to 6 y of age at the Children's Hospital of Philadelphia. RESULTS: At year 2, no significant differences in any measure were observed between the high- and low-risk groups. By year 4, weight, BMI, and lean body mass were greater in the high-risk than in the low-risk children. By year 6, weight was even greater in the high-risk than in the low-risk children (23.4 +/- 6.4 compared with 20.4 +/- 2.1 kg; P < 0.02), and, for the first time, fat mass was greater in the high-risk than in the low-risk children (6.7 +/- 5.7 compared with 3.8 +/- 1.2 kg; P < 0.02). Ten of 33 high-risk children exceeded the 85th percentile of BMI at year 6 compared with 1 of 37 low-risk children (odds ratio = 15.7). Accelerated weight gain was predicted by high-risk group status, greater weight at year 2, and lower family income. CONCLUSION: Anthropometric measures were not significantly different between groups at year 2; weight and lean body mass were greater at years 4 and 6, and fat mass was greater at year 6 in high-risk children.
Authors: S R J Zinkel; R I Berkowitz; A J Stunkard; V A Stallings; M Faith; D Thomas; D A Schoeller Journal: Pediatr Obes Date: 2016-02-22 Impact factor: 4.000
Authors: Tanja V E Kral; Reneé H Moore; Jesse Chittams; Lauren O'Malley; Elizabeth Jones; Ryan J Quinn; Jennifer O Fisher Journal: Appetite Date: 2020-04-11 Impact factor: 3.868
Authors: Robert I Berkowitz; Renee' H Moore; Myles S Faith; Virginia A Stallings; Tanja V E Kral; Albert J Stunkard Journal: Obesity (Silver Spring) Date: 2009-09-24 Impact factor: 5.002
Authors: Tanja V E Kral; Albert J Stunkard; Robert I Berkowitz; Nicolas Stettler; Virginia A Stallings; April Kabay; Myles S Faith Journal: Eat Behav Date: 2009-07-15
Authors: V Svensson; J A Jacobsson; R Fredriksson; P Danielsson; T Sobko; H B Schiöth; C Marcus Journal: Int J Obes (Lond) Date: 2010-09-21 Impact factor: 5.095