| Literature DB >> 15638229 |
S Danese1, F Scaldaferri, A Papa, R Pola, M Sans, G Gasbarrini, P Pola, A Gasbarrini.
Abstract
Besides their classical haemostatic task, platelets are now recognized as novel cells deeply involved in inflammation. Compelling evidence support their role as active player in mucosal tissue injury that occurs in Crohn's disease and ulcerative colitis. In both forms of inflammatory bowel disease platelets contribute to microvascular endothelial activation and recruitment of inflammatory cells, thus fostering and amplifying mucosal inflammation.Entities:
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Year: 2004 PMID： 15638229
Source DB: PubMed Journal: Eur Rev Med Pharmacol Sci ISSN： 1128-3602 Impact factor: 3.507