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Literature DB >> 1563802

A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages.

Abstract

Nitric oxide production by macrophages required either simultaneous or sequential exposure to gamma interferon and lipopolysaccharide; exposure to lipopolysaccharide followed by exposure to gamma interferon gave little response. The apparently evanescent nature of the lipopolysaccharide signal, necessitating persistent stimulation, could be essential to down-regulating nitric oxide production after bacteria are cleared in vivo.

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Year: 1992 PMID： 1563802 PMCID： PMC257128 DOI： 10.1128/iai.60.5.2133-2135.1992

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

19 in total

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16 in total

1. The gills are an important site of iNOS expression in rainbow trout Oncorhynchus mykiss after challenge with the gram-positive pathogen Renibacterium salmoninarum.

Authors: J J Campos-Perez; M Ward; P S Grabowski; A E Ellis; C J Secombes
Journal: Immunology Date: 2000-01 Impact factor: 7.397

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3. Differential regulation of inducible nitric oxide synthase by fibroblast growth factors and transforming growth factor beta in bovine retinal pigmented epithelial cells: inverse correlation with cellular proliferation.

Authors: O Goureau; M Lepoivre; F Becquet; Y Courtois
Journal: Proc Natl Acad Sci U S A Date: 1993-05-01 Impact factor: 11.205

4. Induction of iNOS expression and antimicrobial activity by interferon (IFN)-beta is distinct from IFN-gamma in Burkholderia pseudomallei-infected mouse macrophages.

Authors: P Utaisincharoen; N Anuntagool; S Arjcharoen; K Limposuwan; P Chaisuriya; S Sirisinha
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Authors: H Fahmi; P Ancuta; S Perrier; R Chaby
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Journal: Infect Immun Date: 2009-03-16 Impact factor: 3.441

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Journal: Infect Immun Date: 1995-05 Impact factor: 3.441