| Literature DB >> 15636188 |
S Venkat Reddy1, Pullela V Srinivas, B Praveen, K Hara Kishore, B China Raju, U Suryanarayana Murthy, J Madhusudana Rao.
Abstract
Piper nigrum finds an extensive application in antibacterial preparations belonging to Ayurvedic system of medicine. A bioguided extraction and fractionation of the petroleum ether extract of the berries of P. nigrum afforded 2E, 4E, 8Z-N-isobutyleicosatrienamide (1), pellitorine (2), trachyone (3), pergumidiene (4) and isopiperolein B (5). Pergumidiene and trachyone are isolated for the first time from P. nigrum. All the isolated compounds were active against Bacillus subtilis, Bacillus sphaericus, and Staphylococcus aureus amongst Gram + ve bacteria, and Klebsiella aerogenes and Chromobacterium violaceum among Gram -ve bacterial strains.Entities:
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Year: 2004 PMID： 15636188 DOI： 10.1016/j.phymed.2003.04.004
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340