| Literature DB >> 15636182 |
A G Neto1, A A da Silva Filho, J M L C Costa, A H C Vinholis, G H B Souza, W R Cunha, M L A E Silva, S Albuquerque, J K Bastos.
Abstract
Three different concentrations (1, 10 and 50 microg/ml) of lyophilized hydroalcoholic crude extract of Pfaffia glomerata roots were assayed in vitro against strains of Trypanosoma cruzi (Y) and Leishmania braziliensis. It was observed that P. glomerata hydroalcoholic extract was relatively active within the tested concentrations for L. (V) braziliensis, but inactive against T. cruzi. Despite the fact that both protozoans belong to the Trypanosomatidae family, we suggest that the difference observed for activity should be related to the biological differences between the two parasite species.Entities:
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Year: 2004 PMID： 15636182 DOI： 10.1016/j.phymed.2003.06.005
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340