| Literature DB >> 15635022 |
F Damond1, F Brun-Vezinet, S Matheron, G Peytavin, P Campa, S Pueyo, F Mammano, S Lastere, I Farfara, F Simon, G Chene, D Descamps.
Abstract
We described the baseline polymorphism of the human immunodeficiency virus type 2 (HIV-2) protease gene from 94 treatment-naive patients and the longitudinal follow-up of 17 protease inhibitor-treated patients. Compared to the HIV-2 consensus sequences, baseline polymorphism involved 47 positions. Substitutions selected under treatment were observed at positions corresponding to HIV-1 resistance mutations as well as at positions of currently unknown impact on HIV-1.Entities:
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Year: 2005 PMID: 15635022 PMCID: PMC540186 DOI: 10.1128/JCM.43.1.484-487.2005
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948