| Literature DB >> 15633661 |
Jamalah Munir1, Glenn Preston, Roger Polish.
Abstract
Hepatosplenic T-cell lymphoma is a rare neoplasm characterized by systemic B-symptoms, hepatosplenomegaly, no lymphadenopathy, and lymphomatous infiltrates in the splenic red pulp, hepatic sinusoids, and bone marrow sinuses. The team presents the case of a healthy 30 year old man, active duty Marine, who presented with classic symptoms, yet obtaining a diagnosis took over three months from the onset of symptoms. This clinical entity initially described in 1990, is elusive, with vague and misleading symptoms. Despite aggressive conventional therapy with anthracycline-based regimens and stem cell transplant, prognosis is poor and median survival is less than one yearEntities:
Mesh:
Year: 2004 PMID: 15633661
Source DB: PubMed Journal: Hawaii Med J ISSN: 0017-8594