Literature DB >> 15633238

Acute hepatitis induced by an Aloe vera preparation: a case report.

Christian Rabe1, Annemarie Musch, Peter Schirmacher, Wolfgang Kruis, Robert Hoffmann.   

Abstract

AIM: Aloe vera, plant extracts of Aloe barbadensis miller, is widely used in phytomedicine. The first case of acute hepatitis due to this compound was described.
METHODS: Description of a clinical case.
RESULTS: Hepatitis in a 57-year old female could be linked to the ingestion of Aloe barbadensis miller compounds. The patient's hepatitis resolved completely after discontinuing this medication.
CONCLUSION: The case emphasizes the importance of considering phytopharmaceutical over-the-counter drugs as causative agents of hepatitis.

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Year:  2005        PMID: 15633238      PMCID: PMC4205424          DOI: 10.3748/wjg.v11.i2.303

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  15 in total

1.  The influence of long-term Aloe vera ingestion on age-related disease in male Fischer 344 rats.

Authors:  Yuji Ikeno; Gene B Hubbard; Shuko Lee; Byung Pal Yu; Jeremiah T Herlihy
Journal:  Phytother Res       Date:  2002-12       Impact factor: 5.878

2.  Two functionally and chemically distinct immunomodulatory compounds in the gel of Aloe vera.

Authors:  L A Hart; P H van Enckevort; H van Dijk; R Zaat; K T de Silva; R P Labadie
Journal:  J Ethnopharmacol       Date:  1988 May-Jun       Impact factor: 4.360

3.  Radical scavenging glycoprotein inhibiting cyclooxygenase-2 and thromboxane A2 synthase from aloe vera gel.

Authors:  A Yagi; A Kabash; K Mizuno; S M Moustafa; T I Khalifa; H Tsuji
Journal:  Planta Med       Date:  2003-03       Impact factor: 3.352

4.  The therapeutic potential of Aloe Vera in tumor-bearing rats.

Authors:  M M Corsi; A A Bertelli; G Gaja; A Fulgenzi; M E Ferrero
Journal:  Int J Tissue React       Date:  1998

5.  Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study.

Authors:  T A Syed; S A Ahmad; A H Holt; S A Ahmad; S H Ahmad; M Afzal
Journal:  Trop Med Int Health       Date:  1996-08       Impact factor: 2.622

6.  In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor).

Authors:  H S Kim; S Kacew; B M Lee
Journal:  Carcinogenesis       Date:  1999-08       Impact factor: 4.944

7.  Chemomodulatory action of Aloe vera on the profiles of enzymes associated with carcinogen metabolism and antioxidant status regulation in mice.

Authors:  R P Singh; S Dhanalakshmi; A R Rao
Journal:  Phytomedicine       Date:  2000-06       Impact factor: 5.340

8.  Vitamin C and aloe vera supplementation protects from chemical hepatocarcinogenesis in the rat.

Authors:  N A Shamaan; K A Kadir; A Rahmat; W Z Ngah
Journal:  Nutrition       Date:  1998 Nov-Dec       Impact factor: 4.008

9.  Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes. Bioactivation to genotoxic metabolites.

Authors:  S O Mueller; H Stopper; W Dekant
Journal:  Drug Metab Dispos       Date:  1998-06       Impact factor: 3.922

10.  Hypersensitivity to aloe.

Authors:  D M Morrow; M J Rapaport; R A Strick
Journal:  Arch Dermatol       Date:  1980-09
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  10 in total

1.  Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo.

Authors:  Soyun Cho; Serah Lee; Min-Jung Lee; Dong Hun Lee; Chong-Hyun Won; Sang Min Kim; Jin Ho Chung
Journal:  Ann Dermatol       Date:  2009-02-28       Impact factor: 1.444

2.  Aloe-induced toxic hepatitis.

Authors:  Ha Na Yang; Dong Joon Kim; Young Mook Kim; Byoung Ho Kim; Kyoung Min Sohn; Myung Jin Choi; Young Hee Choi
Journal:  J Korean Med Sci       Date:  2010-02-17       Impact factor: 2.153

Review 3.  Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps.

Authors:  Rolf Teschke; Axel Eickhoff
Journal:  Front Pharmacol       Date:  2015-04-23       Impact factor: 5.810

Review 4.  Alternative Treatments for Minor GI Ailments.

Authors:  A K Mohiuddin
Journal:  Innov Pharm       Date:  2019-07-05

5.  Melanogenesis and antityrosinase activity of selected South african plants.

Authors:  Manyatja Brenda Mapunya; Roumiana Vassileva Nikolova; Namrita Lall
Journal:  Evid Based Complement Alternat Med       Date:  2012-04-24       Impact factor: 2.629

6.  Safety and Efficacy of Medicinal Plants Used to Manufacture Herbal Products with Regulatory Approval in Uganda: A Cross-Sectional Study.

Authors:  Bruhan Kaggwa; Henry Kyeyune; Edson Ireeta Munanura; Godwin Anywar; Stephen Lutoti; Jacqueline Aber; Lynn K Bagoloire; Anke Weisheit; Casim Umba Tolo; Pakoyo Fadhiru Kamba; Patrick Engeu Ogwang
Journal:  Evid Based Complement Alternat Med       Date:  2022-04-13       Impact factor: 2.650

7.  Effects of Aloe vera leaf gel extract on rat peritonitis model.

Authors:  Ayca Altincik; Ferah Sönmez; Cigdem Yenisey; Soner Duman; Ayse Can; Nuriye Akev; Sevin Kirdar; Murat Sezak
Journal:  Indian J Pharmacol       Date:  2014 May-Jun       Impact factor: 1.200

8.  HERBALIFE® ASSOCIATED SEVERE HEPATOTOXICITY IN A PREVIOUSLY HEALTHY WOMAN.

Authors:  Dragan Jurčić; Maruška Gabrić; Rosana Troskot Perić; Ana Marija Liberati Pršo; Jure Mirat; Aleksandar Včev; Ivan Alerić; Barbara Ebling
Journal:  Acta Clin Croat       Date:  2019-12       Impact factor: 0.780

Review 9.  Herbal Hepatotoxicity: Clinical Characteristics and Listing Compilation.

Authors:  Christian Frenzel; Rolf Teschke
Journal:  Int J Mol Sci       Date:  2016-04-27       Impact factor: 5.923

10.  Herb-induced liver injury: Systematic review and meta-analysis.

Authors:  Vinícius Remus Ballotin; Lucas Goldmann Bigarella; Ajacio Bandeira de Mello Brandão; Raul Angelo Balbinot; Silvana Sartori Balbinot; Jonathan Soldera
Journal:  World J Clin Cases       Date:  2021-07-16       Impact factor: 1.337

  10 in total

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