| Literature DB >> 15633061 |
Katharina Marten1, David M Hansell.
Abstract
Macrophage-related pulmonary diseases are a heterogeneous group of disorders characterized by macrophage accumulation, activation or dysfunction. These conditions include smoking-related interstitial lung diseases, metabolic disorders such as Niemann-Pick or Gaucher disease, and rare primary lung tumors. High-resolution computed tomography abnormalities include pulmonary ground-glass opacification secondary to infiltration by macrophages, centrilobular nodules or interlobular septal thickening reflecting peribronchiolar or septal macrophage accumulation, respectively, emphysema caused by macrophage dysfunction, and honeycombing following macrophage-related lung matrix remodeling.Entities:
Mesh:
Year: 2005 PMID: 15633061 DOI: 10.1007/s00330-004-2554-3
Source DB: PubMed Journal: Eur Radiol ISSN: 0938-7994 Impact factor: 5.315