Literature DB >> 1563245

Hyperglycaemia, hypoglycaemia, and blood glucose control in diabetes: symptom perceptions and treatment strategies.

W H Polonsky1, C L Davis, A M Jacobson, B J Anderson.   

Abstract

Recent research has suggested that patients with Type 1 diabetes who are in chronically poor blood glucose control perceive hyperglycaemia differently from those who are in good control. To extend these observations 181 insulin-treated patients with Type 1 or Type 2 diabetes were studied. Patients completed a self-report questionnaire which included items concerning feelings about high and low blood glucose levels and strategies for maintaining blood glucose control. Glycosylated haemoglobin levels were also measured. We hypothesized that level of blood glucose control would: (1) be associated with perceptions of hyperglycaemia and treatment strategies for managing hyperglycaemia and (2) not be associated with perceptions and strategies concerning hypoglycaemia. In comparison with those in 'acceptable' or 'poor' blood glucose control, those in 'good' control perceived symptoms of hyperglycaemia at lower blood glucose levels (p less than 0.001) and felt physically best at lower blood glucose levels (p less than 0.001). They, also began treatment for hyperglycaemia at lower glucose levels (p less than 0.05), set lower minimal (p less than 0.001) and maximal (p less than 0.001) glucose levels as treatment goals, and tested their blood glucose levels more frequently (p less than 0.05). Among Type 1 diabetic patients, those in 'good' control reported experiencing hypoglycaemia at lower glucose levels than those in 'acceptable' or 'poor' control (p less than 0.05). No differences in treatment strategies of hypoglycaemic symptoms were apparent. This study suggests an influence of patients' perceptions of symptoms and treatment in self-care of diabetes.

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Year:  1992        PMID: 1563245     DOI: 10.1111/j.1464-5491.1992.tb01747.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  4 in total

1.  Modelling cost effectiveness of insulin glargine for the treatment of type 1 and 2 diabetes in Canada.

Authors:  Daniel T Grima; Melissa F Thompson; Luc Sauriol
Journal:  Pharmacoeconomics       Date:  2007       Impact factor: 4.981

2.  Change in self-rated general health is associated with perceived illness burden: a 1-year follow up of patients newly diagnosed with type 2 diabetes.

Authors:  Anni Brit Sternhagen Nielsen; Per Jensen; Dorte Gannik; Susanne Reventlow; Hanne Hollnagel; Niels de Fine Olivarius
Journal:  BMC Public Health       Date:  2015-04-30       Impact factor: 3.295

3.  Automated bolus advisor control and usability study (ABACUS): does use of an insulin bolus advisor improve glycaemic control in patients failing multiple daily insulin injection (MDI) therapy? [NCT01460446].

Authors:  David A Cavan; Ralph Ziegler; Iain Cranston; Katharine Barnard; Jacqueline Ryder; Claudia Vogel; Christopher G Parkin; Walter Koehler; Iris Vesper; Bettina Petersen; Robin S Wagner
Journal:  BMC Fam Pract       Date:  2012-10-13       Impact factor: 2.497

4.  High Intensity Aerobic Exercise Training Improves Deficits of Cardiovascular Autonomic Function in a Rat Model of Type 1 Diabetes Mellitus with Moderate Hyperglycemia.

Authors:  Kenneth N Grisé; T Dylan Olver; Matthew W McDonald; Adwitia Dey; Mao Jiang; James C Lacefield; J Kevin Shoemaker; Earl G Noble; C W James Melling
Journal:  J Diabetes Res       Date:  2016-01-18       Impact factor: 4.011

  4 in total

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