Wen-shu Wang1, Ya-wei Zhou, Yun-hua Ye, Nan Du. 1. Key Laboratory of Bioorganic and Molecular Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Abstract
OBJECTIVE: To study flavonoids in Scutellaria barbata and elucidate their structures. METHOD: Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra. RESULT: Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6). CONCLUSION: Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.
OBJECTIVE: To study flavonoids in Scutellaria barbata and elucidate their structures. METHOD: Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra. RESULT: Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6). CONCLUSION:Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.