PURPOSE: To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachment (MHRD) as a result of high myopia. DESIGN: Histologic study. METHODS: We excised three layers of membranes visualized with TA and ICG that were tightly adhering to the retinal surface during vitrectomy and examined them by transmission electron microscopy. RESULTS: The first membrane was made of acellular collagen fibers, suggestive of vitreous, and the second was comprised of parts of fibroblast-like cells and collagen fibrils, suggesting a proliferative epiretinal membrane. The third membrane was an internal limiting membrane. CONCLUSIONS: Multiple components of epiretinal tissue could be delaminated with the assistance of TA and ICG during surgery for myopic MHRD.
PURPOSE: To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachment (MHRD) as a result of high myopia. DESIGN: Histologic study. METHODS: We excised three layers of membranes visualized with TA and ICG that were tightly adhering to the retinal surface during vitrectomy and examined them by transmission electron microscopy. RESULTS: The first membrane was made of acellular collagen fibers, suggestive of vitreous, and the second was comprised of parts of fibroblast-like cells and collagen fibrils, suggesting a proliferative epiretinal membrane. The third membrane was an internal limiting membrane. CONCLUSIONS: Multiple components of epiretinal tissue could be delaminated with the assistance of TA and ICG during surgery for myopic MHRD.
Authors: Kyung Jun Choi; Jung Eun Choi; Hyeon Cheol Roh; Jun Soo Eun; Jong Min Kim; Yong Kyun Shin; Min Chae Kang; Joon Kyo Chung; Chaeyeon Lee; Dongyoung Lee; Se Woong Kang; Baek Hwan Cho; Sang Jin Kim Journal: Sci Rep Date: 2021-11-04 Impact factor: 4.379
Authors: Michele Coppola; Alessandro Rabiolo; Maria Vittoria Cicinelli; Giuseppe Querques; Francesco Bandello Journal: Int J Retina Vitreous Date: 2017-10-02