PURPOSE: To define the prevalence and time course of significant changes in angle of deviation during the first months after the diagnosis of infantile esotropia and to determine whether long-term alignment and sensory outcomes differ when surgical alignment is performed on infants with stable vs unstable angles of deviation. DESIGN: Prospective cohort study. METHODS: setting: Institutional and clinical practice. patient population: Newly diagnosed patients with infantile esotropia (N = 208). observation procedure: Preoperative measurements of the angle of deviation on the initial visit and at approximate six-week intervals until surgery was performed. main outcome measures: Ocular alignment at six weeks, one year, and four years postoperative and stereoacuity at age five to nine years. RESULTS: Overall, 57% of infants had an esodeviation on the second visit that was within 10 prism diopters (p.d.) of the deviation measured on the initial visit (stable group), 33% had an increase of 10 p.d. or more (unstable group), and 11% had a decrease of 10 p.d. or more. Among the 127 patients with additional preoperative visits, many switched between the stable and unstable categories during follow-up. Long-term, stable and unstable preoperative alignment groups had similar postoperative motor alignment, re-operation rates, rates of prescription of hyperopic, or bifocal spectacle correction and stereoacuity. CONCLUSIONS: It may not be necessary to wait for a "stable" angle of esodeviation before surgery since both alignment and sensory outcomes were similar for stable and unstable groups.
PURPOSE: To define the prevalence and time course of significant changes in angle of deviation during the first months after the diagnosis of infantile esotropia and to determine whether long-term alignment and sensory outcomes differ when surgical alignment is performed on infants with stable vs unstable angles of deviation. DESIGN: Prospective cohort study. METHODS: setting: Institutional and clinical practice. patient population: Newly diagnosed patients with infantile esotropia (N = 208). observation procedure: Preoperative measurements of the angle of deviation on the initial visit and at approximate six-week intervals until surgery was performed. main outcome measures: Ocular alignment at six weeks, one year, and four years postoperative and stereoacuity at age five to nine years. RESULTS: Overall, 57% of infants had an esodeviation on the second visit that was within 10 prism diopters (p.d.) of the deviation measured on the initial visit (stable group), 33% had an increase of 10 p.d. or more (unstable group), and 11% had a decrease of 10 p.d. or more. Among the 127 patients with additional preoperative visits, many switched between the stable and unstable categories during follow-up. Long-term, stable and unstable preoperative alignment groups had similar postoperative motor alignment, re-operation rates, rates of prescription of hyperopic, or bifocal spectacle correction and stereoacuity. CONCLUSIONS: It may not be necessary to wait for a "stable" angle of esodeviation before surgery since both alignment and sensory outcomes were similar for stable and unstable groups.
Authors: Stephen P Christiansen; Danielle L Chandler; Jonathan M Holmes; Darron A Bacal; Eileen Birch; Sean P Donahue; Brian G Mohney; Michael X Repka; Lisa C Verderber Journal: J AAPOS Date: 2009-08 Impact factor: 1.220
Authors: Stephen P Christiansen; Danielle L Chandler; Jonathan M Holmes; Robert W Arnold; Eileen Birch; Linda R Dagi; Darren L Hoover; Deborah L Klimek; B Michele Melia; Evelyn Paysse; Michael X Repka; Donny W Suh; Benjamin H Ticho; David K Wallace; Richard Grey Weaver Journal: Ophthalmology Date: 2008-10-29 Impact factor: 12.079
Authors: Jérome Fleuriet; Christy L Willoughby; Rachel B Kueppers; Michael J Mustari; Linda K McLoon Journal: Sci Rep Date: 2020-07-17 Impact factor: 4.379