Literature DB >> 15628995

Significance of the interferon (IFN) in the therapy.

Sabina Mahmutović1, Edina Beslagić.   

Abstract

Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Human IFN are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. Recently are discovered new types of IFNs: Omega and Tau, but bigger than alpha molecules. Also, has been performed the division into two types: I and II. Besides the antiviral and antiproliferative effects, they have also the effect in the treatment of malignant diseases, and act protectively against the radiation.

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Year:  2004        PMID: 15628995      PMCID: PMC7245498          DOI: 10.17305/bjbms.2004.3360

Source DB:  PubMed          Journal:  Bosn J Basic Med Sci        ISSN: 1512-8601            Impact factor:   3.363


  2 in total

Review 1.  Viruses and interferons.

Authors:  G C Sen
Journal:  Annu Rev Microbiol       Date:  2001       Impact factor: 15.500

2.  Intrahepatic expression of pre-S1 and pre-S2 antigens in chronic hepatitis B virus infection in relation to hepatitis B virus replication and hepatitis delta virus superinfection.

Authors:  C M Chu; Y F Liaw
Journal:  Gut       Date:  1992-11       Impact factor: 23.059

  2 in total
  2 in total

1.  Establishment of a stable CHO cell line with high level expression of recombinant porcine IFN-β.

Authors:  Weiye Chen; Wenyan Cao; Huijun Zhao; Qianqian Hu; Linmao Qu; Sen Hu; Jinying Ge; Zhiyuan Wen; Xijun Wang; Haobo Li; Kehe Huang; Zhigao Bu
Journal:  Cytokine       Date:  2011-04-01       Impact factor: 3.861

2.  Interferon-α suppresses invasion and enhances cisplatin-mediated apoptosis and autophagy in human osteosarcoma cells.

Authors:  Jun Zhao; Mingli Wang; Zeng Li; Jingxian Chen; Zongshen Yin; Jun Chang; Dongmei Gao; Shiping Wang
Journal:  Oncol Lett       Date:  2013-12-16       Impact factor: 2.967

  2 in total

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