Literature DB >> 15627084

Demodicosis and rosacea: epidemiology and significance in daily dermatologic practice.

Fabienne Forton1, Marie-Anne Germaux, Thierry Brasseur, Anne De Liever, Marianne Laporte, Chantal Mathys, Ursula Sass, Jean-Jacques Stene, Sylvie Thibaut, Muriel Tytgat, Bruno Seys.   

Abstract

BACKGROUND: Demodicoses are thought to be rare, occurring mainly for patients with immunosuppression.
OBJECTIVE: We sought to demonstrate the high frequency of demodicoses and the overlapping with papulopustular rosacea (PPR) .
METHODS: We conducted a prospective epidemiologic study among 10 dermatologists. High Demodex density (Dd) was confirmed by standardized skin surface biopsy.
RESULTS: In all, 4372 diagnoses, in which 115 were demodicoses, were collected among 3213 patients. Demodicosis was the 9th most frequent diagnosis (13th new). Each dermatologist observed an average of 2.4 demodicoses a week (1.2 new). The proportion of demodicoses varied greatly according to the dermatologist. The general status was good in 110 patients; only 3 had known immunodeficiency. The most frequent symptoms were follicular scales (71%) and telangiectasia (63%). The mean Dd was higher in pityriasis folliculorum (m = 61 D/cm 2 ) than in PPR (m = 36 D/cm 2 ; P = .04); 42 patients with PPR had a high Dd, 6 had a low Dd.
CONCLUSION: Demodicoses are frequent and occur among patients who are immunocompetent. PPR with normal Dd are rare.

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Mesh:

Year:  2005        PMID: 15627084     DOI: 10.1016/j.jaad.2004.05.034

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  29 in total

Review 1.  Rosacea: new and emerging treatments.

Authors:  Farah A Moustafa; Laura F Sandoval; Steven R Feldman
Journal:  Drugs       Date:  2014-09       Impact factor: 9.546

Review 2.  Pathogenic role of Demodex mites in blepharitis.

Authors:  Jingbo Liu; Hosam Sheha; Scheffer C G Tseng
Journal:  Curr Opin Allergy Clin Immunol       Date:  2010-10

3.  Cloning and sequence analysis of chitin synthase gene fragments of Demodex mites.

Authors:  Ya-e Zhao; Zheng-hang Wang; Yang Xu; Ji-ru Xu; Wen-yan Liu; Meng Wei; Chu-ying Wang
Journal:  J Zhejiang Univ Sci B       Date:  2012-10       Impact factor: 3.066

Review 4.  Topical Ivermectin: Data Supporting Dual Modes of Action in Rosacea.

Authors:  James Q Del Rosso
Journal:  J Clin Aesthet Dermatol       Date:  2017-09-01

5.  Facial dermatosis associated with Demodex: a case-control study.

Authors:  Ya-e Zhao; Yan Peng; Xiang-lan Wang; Li-ping Wu; Mei Wang; Hu-ling Yan; Sheng-xiang Xiao
Journal:  J Zhejiang Univ Sci B       Date:  2011-12       Impact factor: 3.066

6.  Sociodemographic characteristics and risk factor analysis of Demodex infestation (Acari: Demodicidae).

Authors:  Ya-e Zhao; Na Guo; Meng Xun; Ji-ru Xu; Mei Wang; Duo-lao Wang
Journal:  J Zhejiang Univ Sci B       Date:  2011-12       Impact factor: 3.066

7.  First report of palpebral conjunctival inflammatory nodule associated with Demodex species.

Authors:  Ying Li; Ga Eon Kim; Kyung Chul Yoon; Won Choi
Journal:  Indian J Ophthalmol       Date:  2018-09       Impact factor: 1.848

8.  Correlation between ocular Demodex infestation and serum immunoreactivity to Bacillus proteins in patients with Facial rosacea.

Authors:  Jianjing Li; Niamh O'Reilly; Hosam Sheha; Raananah Katz; Vadrevu K Raju; Kevin Kavanagh; Scheffer C G Tseng
Journal:  Ophthalmology       Date:  2010-01-15       Impact factor: 12.079

Review 9.  [Ectoparasites. Part 2: Bed bugs, Demodex, sand fleas and cutaneous larva migrans].

Authors:  P Nenoff; W Handrick; C Krüger; J Herrmann; B Schmoranzer; U Paasch
Journal:  Hautarzt       Date:  2009-09       Impact factor: 0.751

10.  Ocular Demodex folliculorum: prevalence and associated symptoms in an Irish population.

Authors:  Orla Murphy; Veronica O'Dwyer; Aoife Lloyd-McKernan
Journal:  Int Ophthalmol       Date:  2018-01-29       Impact factor: 2.031

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