| Literature DB >> 1562597 |
D Sinha1, M R Bakhshi, E P Kirby.
Abstract
A cDNA clone coding for the entire bovine alpha 1-antitrypsin molecule has been isolated from a lambda gt11 bovine liver cDNA library using a human alpha 1-antitrypsin cDNA as a probe. The bovine cDNA was sequenced by the dideoxynucleotide chain termination method. Comparison of the translated amino acid sequence of the bovine alpha 1-antitrypsin with those of the human, baboon, sheep, rat and mouse demonstrates the preservation of most of the critical structural determinants. The bovine and the sheep molecules have a sequence homology of 94% and both the molecules contain four cysteine residues; there is only one cysteine in the others.Entities:
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Year: 1992 PMID： 1562597 DOI： 10.1016/0167-4781(92)90530-d
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002